Dry eye showdown: SYSTANE PRO takes on MIEBO in new trial

NCT ID NCT07243275

Completed Symptom relief Sponsor: Indiana University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 07, 2026 · Updated 3 times

Summary

This study compares two eye drops—SYSTANE PRO and MIEBO—to see if SYSTANE PRO works as well as MIEBO for treating dry eye disease. About 260 adults with moderate dry eye will use one of the two drops for one month. The main goal is to measure changes in dry eye symptoms using a standard questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: SYSTANE PRO (hyaluronate, nano-sized lipids, HP-Guar) and MIEBO (perfluorohexyloctane)
What this could lead to: If SYSTANE PRO works as well as MIEBO, it could offer a more affordable or accessible option for managing dry eye symptoms.
What could go wrong: This is a Phase 4 trial comparing two existing treatments, so no major breakthrough is expected. The study is relatively small and may not show a clear difference between the two drops.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dry eye syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRY EYE DISEASE (DED)

Contacts and locations

Locations

Eye Research Foundation

Newport Beach, California, 92663, United States
Indiana Universtiy School of Optometry

Bloomington, Indiana, 47408, United States
Kannarr Eye Care

Pittsburg, Kansas, 66762, United States
Southern College of Optometry

Memphis, Tennessee, 38104, United States

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