Dry eye showdown: SYSTANE PRO takes on MIEBO in new trial

NCT ID NCT07243275

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two eye drops—SYSTANE PRO and MIEBO—to see if SYSTANE PRO works as well as MIEBO for treating dry eye disease. About 260 adults with moderate dry eye will use one of the two drops for one month. The main goal is to measure changes in dry eye symptoms using a standard questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SYSTANE PRO (hyaluronate, nano-sized lipids, HP-Guar) and MIEBO (perfluorohexyloctane)

What this could lead to

If SYSTANE PRO works as well as MIEBO, it could offer a more affordable or accessible option for managing dry eye symptoms.

What could go wrong

This is a Phase 4 trial comparing two existing treatments, so no major breakthrough is expected. The study is relatively small and may not show a clear difference between the two drops.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dry eye syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Eye Research Foundation

    RECRUITING

    Newport Beach, California, 92663, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Indiana Universtiy School of Optometry

    RECRUITING

    Bloomington, Indiana, 47408, United States

  • Kannarr Eye Care

    RECRUITING

    Pittsburg, Kansas, 66762, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Southern College of Optometry

    RECRUITING

    Memphis, Tennessee, 38104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••