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116076 trials found · Page 3181 of 5804
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Mailed self-test boosts cervical cancer screening in hard-to-reach women
Knowledge-focused CompletedDespite the existence of an effective screening test (pap smear), cervical cancer is, every year in France, the cause of more than 3,000 new cases and 1,100 deaths. But, in France, 4 in 10 women are not screened or not often enough (nearly 7 millions women). It is therefore neces…
Phase: NA • Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Scientists test injecting skin cells to create tougher skin
Knowledge-focused Recruiting nowThis research is being done to determine if investigators can change skin from one type to another. Specifically, investigators are interested in making normal skin into the thicker skin found on our palms and soles.
Phase: PHASE2 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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New test helps assess stroke Patients' thinking, even if they Can't speak
Diagnosis CompletedAfter a CVA, all of the cognitive functions can be affected and analysed, but the presence of a language disorder may considerably hamper the evaluation of other functions. The battery of rapid tests to screen for and quantify cognitive disorders, including the MMSE, the MOCA, t…
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Diagnosis
Last updated Jun 27, 2026 09:03 UTC
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New study tracks colon cancer return rates after advanced surgery
Knowledge-focused CompletedA register-based study is conducted to examine clinical outcomes following a population-based, multi-centred implementation of Laparoscopic Complete Mesocolic Excision (LCME) in the Central Denmark Region, Denmark.
Sponsor: Gødstrup Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Which EBV test is most accurate? study puts three automated assays Head-to-Head
Diagnosis CompletedThis study compared the performance of three automated immunoassays, Architect (Abbott), Immulite (Siemens) and Liaison (Diasorin), for Epstein-Barr virus (EBV) serology. Ninety-one serum samples collected in Amiens University Hospital were analyzed for the presence of Viral Caps…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC
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Massive chest pain registry reveals gaps between guidelines and real-world care in china
Knowledge-focused CompletedChinese Cardiovascular Association is an association dedicated to establishing Chest Pain Centers in hospitals that have basic qualifications and meet pre-designed quality control targets.The vision of Chinese Cardiovascular Association is the cardiovascular health of every Chine…
Sponsor: China Cardiovascular Association • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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New ultrasound software could spot kidney stones without radiation
Diagnosis CompletedThe purpose of this study is to determine whether new software processing of ultrasound images can improve detection and size determination of kidney stones.
Phase: NA • Sponsor: University of Washington • Aim: Diagnosis
Last updated Jul 19, 2026 00:00 UTC
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Pneumonia's hidden danger: 2 million person study links infection to heart attacks and strokes
Knowledge-focused CompletedPneumonia can be acquired in the community (CAP) or during hospitalization (HAP). It is a leading cause of communicable diseases and the second cause of disability-adjusted life-years in the world (Roquilly et al., Shankar-Hari et al.). HAP is a common infectious disease, affecti…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Heart monitoring reveals best position for uterus during C-Section
Knowledge-focused TerminatedThere is currently little information regarding the hemodynamic differences in uterine displacement techniques. Previous studies examining the hemodynamic effects of uterine displacement maneuvers have focused on incidence of hypotension and use of ephedrine. Noninvasive cardiac…
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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MRI scans could reveal how prostate cancer changes after radiation
Knowledge-focused OngoingThe purpose of this study is to better understand prostate cancer changes after radiation treatment, through magnetic resonance imaging (MRI). MRI is an imaging test that allows doctors to see prostate gland without any operation procedures. It can help identifying the tumors in …
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Heart valve durability under review: melody valve in new positions
Knowledge-focused CompletedThe Melody valve has historically been used for pulmonary valve replacements; however it has been more recently used in the mitral and tricuspid positions. This multi-center, retrospective, observational study will review the durability of the Melody valve inserted into the mitra…
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
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New blood test may reduce transfusions in liver transplants
Knowledge-focused CompletedIn current practice, management of coagulation during liver transplantation is performed either through standard coagulation status or with ROTEM® depending on practitioner choice and availability of materials. In this context, the ROTEM® is used since over 2 years by anesthesiol…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Triple imaging technique aims to sharpen prostate cancer detection
Diagnosis TerminatedProstate cancer is the first cancer in humans (25%). The most widely used tracer in oncology, the 18-Fluoro DeoxyGlucose does not allow the study of prostatic neoplasia. On the other hand, Choline, which is an amino alcohol, is involved in the synthesis of cell membranes and has …
Phase: NA • Sponsor: Lille Catholic University • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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New study: can we diagnose CMV in newborns who fail hearing tests within the first month?
Diagnosis CompletedUniversal hearing screening at birth by use of otoacoustic emission (OAE) is now offered in most maternities in France to detect symptomatic hearing impairment at birth but screening of cCMV infection is not coupled with this screening. In this study, the feasibility of achieving…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated Jun 27, 2026 12:01 UTC
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500 breast cancer patients monitored for radiation side effects
Symptom relief OngoingAdjuvant radiotherapy after lumpectomy allows a local long-term control of the order 85 to 95% with a survival rate equivalent to that of the totally mastectomy. The diminution of the local recurrence rate after irradiation post- lumpectomy is also associated to a best global sur…
Sponsor: Centre Oscar Lambret • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Brain's food pleasure linked to insulin resistance in obesity study
Knowledge-focused CompletedObesity is a common problem in the Veteran population as at least 1 in 3 Veterans have obesity. When people with obesity taste food they have less response in areas of the brain that sense pleasure (reward). Decreased pleasure response to food predicts future weight gain. It is n…
Phase: PHASE1 • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Could a simple water trick help more doctors screen for colon cancer?
Knowledge-focused CompletedColonoscopy is a sedated procedure traditionally performed using air insufflation during the insertion phase of the procedure. Recently, the use of water method (eg, water infusion or water exchange techniques) during the insertion phase of colonoscopy has been reported to increa…
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC
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Surgery showdown: which cystocele repair holds up best?
Disease control CompletedThe primary objective of this study is to compare with PFDI-20 questionnaire the functional outcome of laparoscopic sacrocolpopexy and vaginal mesh surgery in the treatment of symptomatic exteriorised cystocele up to 4 years after surgery. The secondary objectives of this study …
Phase: NA • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Early palliative care may boost quality of life in advanced GI cancers
Symptom relief CompletedIn this trial, patients with cancer in the upper gastrointestinal canal who are going to receive first line palliative chemotherapy and patients with colorectal cancer who are going to receive second line palliative chemotherapy will be included. Participating patients will be ra…
Sponsor: Lund University Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 16:42 UTC
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Old antibiotic shows promise for stubborn high blood pressure
Disease control CompletedHypertension (HTN) is the single most prevalent risk factor for cardiovascular disease, diabetes, obesity and metabolic syndrome. Recent American Heart Association (AHA) statistics indicate that one-third of all adults in the United States of America suffer from HTN. Despite adva…
Phase: PHASE2 • Sponsor: University of Florida • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC