Freezing spray may prevent airway scarring from returning

NCT ID NCT06085209

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether adding a liquid nitrogen cryospray to standard treatments (balloon dilation or laser incision) can prevent benign airway stenosis from coming back within 6 months. About 12 adults with significant tracheal narrowing will receive the cryospray during a bronchoscopy. The main goal is to see if the airway stays more open on CT scans compared to personal best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

liquid nitrogen cryospray (truFreeze device)

What this could lead to

If it works, this could point toward a better way to prevent airway narrowing from coming back after treatment, reducing the need for repeat procedures.

What could go wrong

This is a very early pilot study with only 12 people, so results may not apply broadly. The added cryospray could cause side effects like tissue damage or infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

tracheal stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Virgnia Commonwealth University

    RECRUITING

    Richmond, Virginia, 23298, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••