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116076 trials found · Page 3140 of 5804
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New MRI scan could revolutionize kidney disease monitoring
Knowledge-focused OngoingResearch question: Can multiparametric renal Magnetic Resonance Imaging (MRI) provide structural and functional assessment of the kidneys to deliver prognostic information and guide treatment options in chronic kidney disease (CKD)? Aims and objectives: 1. To establish a multip…
Sponsor: University Hospitals of Derby and Burton NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Crunch test: could hearing loss steal the joy of a crispy biscuit?
Knowledge-focused Recruiting nowBackground. Decreased taste and smell contribute to loss of appetite (anorexia), and the resulting protein-energy malnutrition increases the frailty of the elderly. The risk of falls, disability, infections and depression often requires them to be institutionalized. Elderly, unde…
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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European registry aims to improve care for pancreatic enzyme deficiency
Knowledge-focused CompletedEURO-PEI is a multicentre, observational registry conducted at eight specialist pancreatic centres in Spain, Hungary, France, Italy, and the United Kingdom. The registry was designed to capture routine specialist practice without protocol-mandated diagnostic testing, PERT dosing,…
Sponsor: Hospital Clinico Universitario de Santiago • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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New study tests stronger ankle surgery for people with loose joints
Disease control Recruiting nowGJL is a risk factor for postoperative recurrent instability following an MBR for CLAI. Additional suture tape augmentation has been suggested to provide more strength and stability. However, the outcomes of the MBP with suture tape augmentation were unknown, which requires furth…
Sponsor: Peking University Third Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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New wearable device aims to ease lymphedema swelling
Symptom relief CompletedA Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of Koya Dayspring Active Wearable Compression Technology for Treating Lower Extremity Lymphedema
Phase: NA • Sponsor: Koya Medical, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Can a mirror and mild zaps restore arm movement after stroke?
Symptom relief CompletedIn this study, it was aimed to evaluate whether or not NMES in front of the mirror brings an additional benefit to mirror therapy alone or NMES alone on upper extremity motor and functional development, spasticity, anxiety, depression, cognitive function and activities of daily l…
Phase: NA • Sponsor: Bursa Yuksek Ihtisas Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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New camera could help surgeons see hidden brain tumors
Knowledge-focused OngoingLow grade glioma (LGG) is a slowly evolving, highly invasive intrinsic brain tumor displaying only subtle tissue differences with the normal surrounding brain, hampering the attempts to visually discriminate tumor from normal brain, especially at the border interface. This makes …
Phase: NA • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Coaching program aims to ease burnout among mental health peer workers
Symptom relief CompletedThe role of peer support specialists (PSS) has burgeoned in the mental health field. Peer support specialists are individuals with a psychiatric condition who are in recovery and who are employed to provide various kinds of tangible and other supports to individuals with psychiat…
Phase: NA • Sponsor: Boston University Charles River Campus • Aim: Symptom relief
Last updated Jul 22, 2026 00:00 UTC
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New wrinkle treatment aims to rival botox in Head-to-Head trial
Symptom relief CompletedTo evaluate the efficacy and safety of botulinum toxin type A for injection INI101 compared to BOTOX® in subjects with moderate to severe glabellar lines.
Phase: PHASE3 • Sponsor: INIBIO Co., Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Ancient healing meets modern science: korean medicine tested for facial paralysis
Symptom relief Recruiting nowThis is an observational study that evaluate the effectiveness and safety of Korean integrative treatments in patients with peripheral facial nerve palsy. Adulthood patients aged between 19 to 69 who were diagnosed with peripheral facial nerve palsy and receive Korean integrative…
Sponsor: Jaseng Medical Foundation • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Surgical tool under scrutiny: could it spread cancer cells?
Knowledge-focused Recruiting nowThis is a prospective, multi-center, randomized non-inferiority phase III study to evaluate if patients undergoing a minimally invasive surgery for early stage uterine cancer have cancer cells in the fluid that is obtained at the time of their surgery when a uterine manipulator i…
Phase: NA • Sponsor: Anthony Costales, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Phone-Based wellness program aims to ease breast cancer journey
Symptom relief OngoingThis clinical trial aims to develop a lifestyle program to improve clinical outcomes in women with breast cancer who do not have a healthy diet, regular exercise habits, or ways to manage their stress well. The program will include support and counseling in healthy eating, physic…
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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New triple inhaler shows promise for advanced COPD lungs
Disease control CompletedThe objective of this clinical study was to evaluate the tolerability, safety, and efficacy of stepping up from fluticasone propionate (FP)/salmeterol (SLM) dry-powder inhaler (DPI) (SERETIDE™ DISKUS™) to extrafine beclometasone dipropionate (BDP)/formoterol fumarate (FF)/glycopy…
Phase: PHASE3 • Sponsor: Chiesi Farmaceutici S.p.A. • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Surgery or medicine? study aims to find best path for pelvic floor patients
Knowledge-focused CompletedThis study evaluate the rate of occurrence of fecal incontinence in patients who had surgery for posterior pelvic static disorder versus those with medical management. The aim is also to assess the natural history of constipation symptoms and quality of life in patients with pos…
Sponsor: Rennes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Scientists compare three knee implant designs to see which moves most naturally
Knowledge-focused CompletedThe objective of this study is to determine and compare the in vivo kinematics and vibroarthrography (VAG) signals for subjects implanted with Journey II Bi-Cruciate Stabilized (BCS), CR (Cruciate Retaining), and Bi-Cruciate Retaining (XR) TKAs.
Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Low-Carb paradox: study probes why some see blood sugar spike
Knowledge-focused CompletedThe purpose of this project was to elucidate the phenomenon of elevated blood glucose in the context of dietary carbohydrate restriction. Accordingly, we sought to quantify glucagon, and related hormones, between individuals that are adhering to a low-carbohydrate diet that manif…
Phase: NA • Sponsor: Brigham Young University • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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Can a navigator help minority kids with ADHD stay on track?
Symptom relief OngoingADHD is the most common pediatric neurodevelopmental disorder and is associated with significant long-term impairments. Current guidelines recommend stimulant medication and/or behavioral therapy as first-line treatments for ADHD. Despite evidence that consistent treatment is imp…
Phase: NA • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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New finger device could replace painful blood pressure needles for kids
Diagnosis CompletedThis is a prospective observational study to investigate if a non-invasive blood pressure monitoring device, the CareTaker Pulse Decomposition Analysis (PDA), can accurately measure blood pressure in children when compared to an arterial line. Enrolled patients will have the Care…
Phase: NA • Sponsor: Boston Children's Hospital • Aim: Diagnosis
Last updated Jul 25, 2026 00:00 UTC
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Does a Real-Time tissue check during lung biopsy boost genetic testing success?
Knowledge-focused ENROLLING_BY_INVITATIONThis research study is being done to compare two ways to conduct bronchoscopic biopsy of lymph nodes and other structures in the chest (i.e. the presence or absence of an on-site cytotechnologist performing a limited microscopic evaluation to provide non-binding feedback on speci…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Shorter hospital stays with day treatment may help kids with anorexia recover better
Disease control Recruiting now"In so-called ""early onset"" anorexia nervosa (AN), a rare and severe form affecting 8-13 year olds, experts recommend that, as soon as possible, treatment should take place on an outpatient basis, at an age when separation from the usual environment would be particularly unplea…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC