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127005 trials found · Page 2347 of 6351
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Could cold platelets stop bleeding better in heart surgery?
Disease control OngoingPLTS-1 is a multicentre, randomized, controlled, pilot trial, using a conventional, parallel group, two-armed design at 2 cardiac surgery centres in Canada. The study is designed to assess the feasibility of a future, definitive RCT to determine the non-inferiority of cold-stored…
Phase 2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Magnetic pulses may unlock secrets of language after stroke
Knowledge-focused Recruiting nowThis study will examine the effect of TMS on people with stroke and aphasia as well as healthy individuals.
Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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New drug combo aims to fight resistant prostate cancer
Disease control Recruiting nowThe purpose of this study is to find out whether tinengotinib in combination with abiraterone acetate and prednisone or enzalutamide is a safe treatment that causes few or mild side effects in people with metastatic castration-resistant prostate cancer (mCRPC).
Phase 1/2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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AI boosts skin diagnosis accuracy for GPs in small trial
Diagnosis CompletedThis study aims to determine if an artificial intelligence (AI) medical device can help primary care doctors more accurately identify and manage various skin conditions. Skin issues are a frequent reason for doctor visits, but differences in expertise between general practitioner…
Sponsor: AI Labs Group S.L • Aim: Diagnosis
Last updated Jun 27, 2026 09:07 UTC
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ECMO patients may get safer blood thinner in new trial
Disease control Recruiting nowThe purpose of this study was to evaluate the efficacy and safety of bivalirudin in anticoagulation therapy in patients with extracorporeal membrane oxygenation (ECMO) compared with unfractionated heparin.
Sponsor: Xiaotong Hou • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Home rehab trial could change Post-Hospital recovery
Disease control OngoingWe will perform a parallel-group multicenter patient-level randomized controlled evaluation of skilled nursing facility care at home. Patients typically referred to a skilled nursing facility following hospitalization will be eligible for enrollment. Instead of admission to a ski…
Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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New lens offers sharper sight at all distances for cataract patients
Symptom relief CompletedProspective, multicenter, bilateral, interventional, controlled, masked (sponsor, subjects, and evaluators), randomized clinical trial.
Sponsor: Johnson & Johnson Surgical Vision, Inc. • Aim: Symptom relief
Last updated Aug 26, 2026 00:00 UTC
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Brain-Safe bypass: smart monitor aims to personalize blood pressure during heart surgery
Knowledge-focused Recruiting nowA single-center, prospective, observational pilot of the Cerebral Adaptive Index for assessing personalized blood pressure targets
Sponsor: Becton, Dickinson and Company • Aim: Knowledge-focused
Last updated Jul 10, 2026 00:00 UTC
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Can a smart device spot a hidden heart problem?
Diagnosis CompletedThe aim of the study is to evaluate the performance of Withings SCT02 with embedded Withings ECG-app in the automatic detection of atrial fibrillation
Sponsor: Withings • Aim: Diagnosis
Last updated Jun 27, 2026 09:06 UTC
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New hope for advanced cancer: KQB198 trial launches
Disease control OngoingThe goal of this clinical trial is to learn if KQB198 works to treat advanced solid tumor cancer in adults. It will also learn about the safety of KQB198. The main questions it aims to answer are: * What is the safe dose of KQB198 by itself or in combination with other anti-canc…
Phase 1 • Sponsor: Kumquat Biosciences Inc. • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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Could a daily postbiotic help fight yeast infections?
Disease control CompletedThis project aims to study the efficacy of oral administration of postbiotic at 1g/day as an adjunct treatment against vaginal candidiasis in women for 4-weeks compared to placebo.
Phase 2/3 • Sponsor: Min-Tze LIONG • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Can a national registry unlock better care for kids with eosinophilic esophagitis?
Knowledge-focused CompletedThe aim of the study is to assess the incidence of EZP in Poland in the pediatric population and characteristics of Polish patients with EZP, i.e. their demographic, clinical, endoscopic and histological features. Another important objective of the study is to identify areas wher…
Sponsor: Medical University of Warsaw • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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Herbal capsule could lower heart inflammation in coronary disease
Disease control Recruiting nowThis trials aims to assess, in 240 eligible patients with coronary heart disease, the effects on level of high-sensitivity C-reactive protein (hsCRP) changes from baseline to 12 weeks of Xuesaitong Soft Capsules.
Phase 4 • Sponsor: China National Center for Cardiovascular Diseases • Aim: Disease control
Last updated Jun 26, 2026 14:54 UTC
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Self-Sampling could boost cervical cancer screening in older women
Diagnosis CompletedCervical cancer remains a major cause of mortality in low- and middle-income countries, especially among women aged 50 years and older who are often under-screened. In post-menopausal women, the transformation zone is frequently not visible, which makes visual inspection with ace…
Sponsor: University Hospital, Geneva • Aim: Diagnosis
Last updated Jun 27, 2026 08:12 UTC
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New heart test could predict future attacks
Diagnosis Recruiting nowA prospective, single-center, observational study aiming to assess the predictive role of flow mediated dilatation in acute coronary syndromes, combined with echocardiographic and biochemical indices. The novel Cor-IS technology will also be evaluated.
Sponsor: Aristotle University Of Thessaloniki • Aim: Diagnosis
Last updated Jun 27, 2026 09:09 UTC
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Hidden danger: microplastics found in brain clots may worsen stroke outcomes
Knowledge-focused OngoingThis observational study investigates the presence of micro- and nanoplastics in surgically removed intracerebral hematomas and their association with neurological outcomes in patients with spontaneous intracerebral hemorrhage. Microplastics have recently been identified in huma…
Sponsor: University of Campania Luigi Vanvitelli • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Brain zapping study seeks to unravel why Parkinson's patients lose balance
Knowledge-focused Recruiting nowThe purpose of this project is to use transcranial magnetic stimulation (TMS) to explore the state of excitability of corticocortical and corticofugal (cortex to spinal cord, cortex to brainstem to spinal cord) pathways that project to muscles that control the legs and trunk in p…
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Could a smarter breathing machine boost survival after cardiac arrest?
Knowledge-focused CompletedThe main goal of this observational study is the evaluation of Chest Compression Synchronized Ventilation (CCSV) regarding oxygenation in terms of PaO2 assessed by routine blood gas analysis, hemodynamic effects, 30-day outcome and safety in comparison to Intermittent Positive Pr…
Sponsor: Medical University of Vienna • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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HIV and fatty liver: a hidden link under the microscope
Knowledge-focused Recruiting nowThis study aims to identify the risk factors that lead to the development of metabolic liver disease in people who have been newly diagnosed with HIV. The research will take place across 9 centers in Türkiye and plans to include 250 newly diagnosed individuals with HIV, alongside…
Sponsor: Yaşar Bayındır, MD • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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A quick ultrasound during labor may predict perineal tears and C-Section risk
Knowledge-focused CompletedIntrapartum ultrasonography has been used as a current alternative method to vaginal examination. In this study, the role of head-perineum distance (HPD) measured by transperineal ultrasonography (TPU) at the beginning of the active phase in predicting maternal outcomes related t…
Sponsor: Gaziosmanpasa Research and Education Hospital • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC