Brain-Safe bypass: smart monitor aims to personalize blood pressure during heart surgery

NCT ID NCT06492746

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study tests a new monitoring tool called the Cerebral Adaptive Index (CAI) that may help doctors set personalized blood pressure targets during heart surgery. The tool tracks brain blood flow in real time. Researchers will observe 120 adults aged 45 and older who are at high risk for brain blood vessel disease and are having heart surgery with a heart-lung machine. The goal is to see how often the CAI signals potential brain stress during standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Cerebral Adaptive Index (CAI) monitoring device
What this could lead to
If successful, this could lead to personalized blood pressure management during heart surgery, potentially reducing brain injury risk.
What could go wrong
This is a small pilot study, so results may not be conclusive. The index is new and unproven, and may not improve outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Northwestern University Hospital

    RECRUITING

    Evanston, Illinois, 60611, United States

    Contact

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