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Your eyes could reveal Alzheimer's: new study uses retinal imaging to spot brain disease

NCT ID NCT03233646

First seen Feb 04, 2026 · Last updated Jun 23, 2026 · Updated 14 times

Summary

This study uses non-invasive eye scans (OCT and OCTA) to look for changes in the retina that might be linked to brain diseases like Alzheimer's, Parkinson's, and multiple sclerosis. Researchers aim to find early markers that could help diagnose or track these conditions. The study will include 2,000 adults with and without neurodegenerative diseases.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Duke University Medical Center

    RECRUITING

    Durham, North Carolina, 27705, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple, non-invasive eye test to help diagnose or monitor brain diseases like Alzheimer's and Parkinson's earlier.

What could go wrong

This is an observational study, not a treatment trial. It may not find reliable biomarkers, and results may not apply to all patients or stages of disease.

Conditions

The condition(s) this trial relates to.

Alzheimer disease amyotrophic lateral sclerosis Brain Concussion Brain Injuries, Traumatic Cognitive Dysfunction Down syndrome frontotemporal dementia Huntington disease Lewy body dementia Lewy Body Disease multiple sclerosis neurodegenerative disease Parkinson disease post-traumatic stress disorder traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.