FRONTOTEMPORAL DEMENTIA
Clinical trials for FRONTOTEMPORAL DEMENTIA explained in plain language.
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Brain-Delivered gene therapy tested to halt rare, Early-Onset dementia
Disease control Recruiting nowThis early-stage study is testing a one-time gene therapy called AVB-101 for people with a specific genetic form of frontotemporal dementia (FTD-GRN). The therapy is delivered directly into the brain during a single procedure, aiming to restore a missing protein and potentially s…
Matched conditions: FRONTOTEMPORAL DEMENTIA
Phase: PHASE1, PHASE2 • Sponsor: AviadoBio Ltd • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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Brain injection trial aims to slow devastating dementia
Disease control Recruiting nowThis early-stage study is testing a one-time gene therapy injection for adults with specific genetic forms of frontotemporal dementia (FTD). The treatment, called PBFT02, aims to deliver a working copy of a missing or faulty gene directly to the brain to potentially slow disease …
Matched conditions: FRONTOTEMPORAL DEMENTIA
Phase: PHASE1, PHASE2 • Sponsor: Passage Bio, Inc. • Aim: Disease control
Last updated Apr 02, 2026 14:58 UTC
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Virtual lifeline for dementia caregivers: can video groups ease the burden?
Symptom relief Recruiting nowThis study is testing a video-based support program called STELLA-FTD for family members caring for someone with frontotemporal dementia (FTD). The program aims to help caregivers better manage difficult behaviors and reduce their own stress through group video sessions. Research…
Matched conditions: FRONTOTEMPORAL DEMENTIA
Phase: NA • Sponsor: Oregon Health and Science University • Aim: Symptom relief
Last updated Apr 03, 2026 14:43 UTC
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Brain scan study tests drug for dementia mood symptoms
Symptom relief Recruiting nowThis study is testing if a medication called vortioxetine can help improve mood symptoms like depression and anxiety, as well as thinking skills, in people with early-stage behavioral variant frontotemporal dementia (bvFTD). Researchers will give participants the drug for 12 week…
Matched conditions: FRONTOTEMPORAL DEMENTIA
Phase: PHASE2 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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Zapping the brain to fight forgetfulness: new hope for dementia patients?
Symptom relief Recruiting nowThis study is testing whether a gentle, non-invasive brain stimulation technique can improve symptoms like memory loss and confusion in people with Alzheimer's disease, Lewy body dementia, and other related conditions. Researchers will compare the effects of real stimulation to a…
Matched conditions: FRONTOTEMPORAL DEMENTIA
Phase: NA • Sponsor: Kuopio University Hospital • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Scientists seek clues to devastating brain diseases in new NIH study
Knowledge-focused Recruiting nowThis study aims to better understand related brain diseases like ALS (Lou Gehrig's disease) and frontotemporal dementia. Researchers are recruiting 360 adults who have been diagnosed with these conditions or carry a genetic risk. Participants undergo detailed testing, including b…
Matched conditions: FRONTOTEMPORAL DEMENTIA
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC
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Eye scans could spot Alzheimer's years before symptoms
Knowledge-focused Recruiting nowThis study aims to see if detailed pictures of the back of the eye (the retina) can reveal early signs of brain diseases like Alzheimer's and Parkinson's. Researchers will use special, non-invasive camera scans on 2000 people, both with and without these conditions. The goal is t…
Matched conditions: FRONTOTEMPORAL DEMENTIA
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:41 UTC
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Scientists hunt for early warning signs of dementia
Knowledge-focused Recruiting nowThis study aims to create a better prediction model for how memory and thinking problems worsen over time in people with early dementia or mild cognitive impairment. Researchers will collect blood samples, perform brain scans, conduct memory tests, and gather information from clo…
Matched conditions: FRONTOTEMPORAL DEMENTIA
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:41 UTC