FRONTOTEMPORAL DEMENTIA

This study tested the safety and effects of an experimental drug called AL001 in people who carry genetic mutations that cause frontotemporal dementia. The drug was given intravenously to 33 participants over nearly two years to see how their bodies handled it and to measure cert…

This study tested a remote care program for people with dementia and their family caregivers. Over 1,200 patient-caregiver pairs across six U.S. health systems received 12 months of support via phone and web from trained navigators supervised by dementia specialists. The research…

This study tested whether an online tool called WeCareAdvisor could help caregivers of people with dementia. 262 caregivers used the web-based tool for 3-6 months to get advice on managing challenging behaviors like agitation or anxiety. Researchers measured if the tool reduced c…

This study tested a program called STELLA-FTD, which uses video calls to connect family caregivers with trained guides. The goal was to teach caregivers strategies to manage difficult behaviors in their loved ones with frontotemporal dementia and to reduce their own stress and bu…

This study aimed to understand what daily life is like for people living with or at genetic risk for a specific type of dementia called behavioral variant frontotemporal dementia (bvFTD). Researchers conducted phone interviews with 26 participants to learn about their challenges,…

This small pilot study tested whether wearable sensors could measure apathy (loss of motivation) in people with frontotemporal dementia during everyday activities. Researchers compared 14 participants—some with dementia and some healthy—to see if sensors could detect patterns of …

This research study aimed to understand how the brain's frontal lobe works during thinking tasks like categorization and analogical reasoning. Researchers compared brain activity in 130 participants—some with frontal dementia conditions and some healthy volunteers—using cognitive…