Zhejiang University

This is an early study to test the safety and see if a new drug called SYNCAR-100 might help adults with a specific type of B-cell leukemia that has come back or hasn't responded to other treatments. The drug is based on circular RNA technology and is given once a week for four w…

This is an early-stage safety study testing a new type of treatment called CNCT19 CAR-T cell therapy for advanced liver cancer. Researchers will collect immune cells from 12 patients, modify them in a lab to better target cancer, and then infuse them back. The main goal is to fin…

This study is testing a new first-line treatment for advanced colorectal cancer that aims to avoid chemotherapy. It combines targeted drugs that block cancer growth signals with or without immunotherapy drugs that help the immune system fight cancer. The goal is to see if this ch…

This study is testing a new combination of drugs for people with a specific type of pancreatic cancer that is difficult to remove with surgery. It aims to see if adding the experimental drug HRS-4642 to standard treatments can better control the cancer and make surgery possible. …

This early-stage study is testing a new cell therapy for adults with a rare and aggressive blood cancer called eosinophilic leukemia that has not responded to standard treatments. Doctors will modify a patient's own immune cells (called CAR-T cells) to recognize and attack the ca…

This study is testing a combination of three treatments given before surgery for locally advanced rectal cancer. The goal is to see if adding an immunotherapy drug (serplulimab) and an anti-inflammatory drug (celecoxib) to standard chemotherapy (CAPEOX) can shrink tumors more eff…

This is an early-stage study testing a new type of personalized immune cell therapy (called CAR-T) for people with advanced liver cancer that has stopped responding to standard treatments. Doctors will collect a patient's own immune cells, modify them in a lab to target a specifi…

This study is testing if a newer, less invasive surgery for colon cancer works as well as or better than the standard surgery. Researchers will compare two types of laparoscopic (keyhole) surgeries to see which one helps patients live longer without the cancer returning and gives…

This study is testing an experimental cell therapy called CD19 CAR-T for adults newly diagnosed with a specific, aggressive type of leukemia (Philadelphia chromosome-positive ALL). The therapy involves collecting and genetically modifying a patient's own immune cells to better fi…

This study is testing whether a new combination of airway devices can prevent dangerous drops in blood oxygen levels in morbidly obese patients during sedated gastrointestinal endoscopy. Researchers will compare the new approach, which uses a special airway tube plus high-flow ox…

This early-phase study is testing a new type of cell therapy called Meta10-19 CAR-T for people with moderate to severe active lupus. The therapy involves taking a patient's own immune cells, modifying them in a lab to better target the B cells thought to drive lupus, and then inf…

This study is testing if a high-flow nasal oxygen device is better than a standard one at preventing dangerously low oxygen levels in critically ill patients during sedated endoscopy. It will involve 450 patients with serious health conditions like liver cirrhosis. The goal is to…

This study is testing whether adding a new drug called IBI343 to standard chemotherapy helps control advanced pancreatic cancer. It will involve 64 patients whose cancer has a specific marker called CLDN18.2. The main goals are to see if the combination is safe and if it shrinks …

This study is testing a new combination of drugs for people with advanced pancreatic cancer that has spread and has a specific genetic change called KRAS G12D. The goal is to see if adding a new drug called HRS-4642 to standard chemotherapy and another targeted drug can better co…

This study is testing a new medical device designed to help obese patients breathe better and maintain safe oxygen levels while they are sedated for stomach and colon exams. The device combines several functions like oxygen support and airway management into one tool. Researchers…

This is the first human study to test the safety and early effects of an experimental cell therapy called KSV01. It's for adults aged 18-80 whose B-cell acute lymphoblastic leukemia has come back or hasn't responded to standard treatments. The main goal is to find a safe dose by …

This early-stage study is testing a new type of cell therapy called C-CAR031 for people with advanced liver cancer that has not responded to standard treatments. Doctors will collect and modify a patient's own immune cells to better attack cancer, then infuse them back. The main …

This study aims to create a simple scoring system that helps doctors predict which patients may have food or liquid remaining in their stomach before undergoing sedated gastroscopy (a camera examination of the stomach). Researchers will follow 5,000 patients to identify risk fact…

This study is testing an artificial intelligence (AI) tool called PANDA Pro to see if it can help doctors detect pancreatic cancer earlier on standard CT scans. It will involve up to 100,000 patient scans from a major hospital to check if the AI can find cancers that might otherw…

This large study aims to find the most effective way to screen average-risk people for colorectal cancer. It will compare three methods: a one-time colonoscopy, yearly stool tests, and a new approach combining yearly stool and blood tests. The main goal is to see if the simpler s…

This study is testing whether a special high-flow nasal oxygen device can prevent dangerous drops in oxygen levels during sedated endoscopy procedures. The research focuses on 600 patients who are at high risk for obstructive sleep apnea and are scheduled for gastrointestinal exa…

This study is testing if adding a mild, painless electrical stimulation on specific wrist and hand pressure points (acupoints) can work better than standard triple-drug therapy alone at preventing nausea and vomiting after surgery. It will involve 780 women at high risk for this …

This study looks back at medical records to understand how often and why patients develop voice problems or throat injuries after having a breathing tube placed during surgery. Researchers will analyze data from 1,200 patients who had surgery for conditions like cancer and later …