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New gene therapy injection shows promise for tough leukemia

NCT ID NCT07246707

First seen Jan 11, 2026 · Last updated Jun 19, 2026 · Updated 28 times

Summary

This early-phase trial is testing a new gene therapy called KSV01 for patients with B-cell acute lymphoblastic leukemia that has come back or not responded to standard treatment. The study will enroll 30 adults aged 18 to 80 to check if the treatment is safe and tolerable, and to see if it can help control the disease. KSV01 uses a modified virus to deliver genetic instructions to the patient's own cells to fight the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • First Affiliated Hospital of Zhejiang University

    RECRUITING

    Hangzhou, China

    Contact Phone: •••-•••-••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

KSV01 injection (a gene therapy using a modified virus to target cancer cells)

What this could lead to

If successful, this could lead to a new treatment option for patients with hard-to-treat B-cell acute lymphoblastic leukemia.

What could go wrong

This is a very early phase 1 trial with only 30 people, so it's too soon to know if it works. There are risks like severe immune reactions or nerve problems.

Conditions

The condition(s) this trial relates to.

B-cell acute lymphoblastic leukemia precursor B-cell acute lymphoblastic leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.