Xijing Hospital Of Digestive Diseases

This study tests whether adding fenofibrate to the standard drug ursodeoxycholic acid (UDCA) helps people with primary biliary cholangitis (PBC) who don't respond well to UDCA alone. About 150 adults with PBC will receive either the combination or a placebo for up to 36 weeks. Th…

This study is for adults with primary biliary cholangitis (PBC) who have not yet been treated. It compares the drug fenofibrate to the standard medicine, UDCA, to see which better helps the liver work normally. About 132 participants will take one of the two drugs daily for a yea…

This study looks at the long-term safety of combining fenofibrate with ursodeoxycholic acid in people with primary biliary cholangitis (PBC), a chronic liver disease. Researchers will monitor 150 participants for side effects and track outcomes like death, need for liver transpla…

This study looks at the long-term safety of adding fenofibrate to standard ursodeoxycholic acid treatment for people with primary biliary cholangitis (PBC), a chronic liver disease. About 300 adults who have already completed a prior fenofibrate study will take the combination an…

This study is for adults with primary biliary cholangitis (a chronic liver disease) who have cirrhosis and did not respond well to the standard drug ursodeoxycholic acid. Researchers want to see if adding fenofibrate to their treatment can improve liver function and reduce sympto…

This study tests whether upadacitinib, a newer pill, works as well as infliximab, an older infusion, for people with severe ulcerative colitis who didn't improve with first treatment. About 226 adults will be randomly assigned to one of the two drugs for 3 months. The goal is to …

This study tests whether a probiotic called Clostridium butyricum can improve anxiety and depression in people with functional dyspepsia (a stomach disorder with no clear cause). 180 adults will receive either the probiotic or a placebo for 4 weeks, alongside standard stomach med…

This study tests whether a probiotic called Bacillus coagulans can improve anxiety and depression in people with functional dyspepsia (a stomach disorder with no clear cause). About 180 adults will receive either the probiotic or a placebo for 4 weeks, alongside standard stomach …

This study tests whether a non-invasive brain stimulation technique called tACS can help adults with severe constipation that hasn't improved with standard treatments, especially when they also have physical symptoms linked to stress. About 60 participants will receive either rea…

This study tests a non-invasive device that gently stimulates a nerve in the ear (taVNS) to see if it can improve bowel movements in adults with constipation that hasn't responded to standard treatments. One hundred participants will be randomly assigned to receive either the act…