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New hope for severe colitis: which drug works best?

NCT ID NCT07550673

First seen Apr 29, 2026 · Last updated May 22, 2026 · Updated 4 times

Summary

This study tests whether upadacitinib, a newer pill, works as well as infliximab, an older infusion, for people with severe ulcerative colitis who didn't improve with first treatment. About 226 adults will be randomly assigned to one of the two drugs for 3 months. The goal is to see which one reduces symptoms like bloody diarrhea and belly pain faster, and to check for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • 3201 Hospital

    RECRUITING

    Hanzhong, Shaanxi, 710005, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ankang Central Hospital

    RECRUITING

    Ankang, Shaanxi, 725000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shaanxi Provincial Nuclear Industry 215 Hospital

    RECRUITING

    Xianyang, Shaanxi, 712000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xijing Hosipital of Digestive Disease

    RECRUITING

    Xi'an, Shaanxi, 710005, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.