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Double-Drug attack may tame severe colitis flares

NCT ID NCT07297069

First seen Jan 08, 2026 · Last updated Apr 30, 2026 · Updated 13 times

Summary

This study looks at adults hospitalized with a severe flare of ulcerative colitis that didn't get better with IV steroids. It compares taking a combination of two drugs (infliximab and tofacitinib) versus either drug alone. The goal is to see if the combo leads to faster symptom relief and gut healing over 10 weeks, with fewer side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asian Institute of Gastroenterology

    Hyderabad, Telangana, 500082, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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