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New combo therapy offers hope for stubborn liver disease

NCT ID NCT05751967

First seen Jan 11, 2026 · Last updated May 23, 2026 · Updated 15 times

Summary

This study tests whether adding fenofibrate to the standard drug ursodeoxycholic acid (UDCA) helps people with primary biliary cholangitis (PBC) who don't respond well to UDCA alone. About 150 adults with PBC will receive either the combination or a placebo for up to 36 weeks. The goal is to see if the combo normalizes key liver blood tests and improves quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Nanjing Drum Tower Hospital

    RECRUITING

    Nanjing, Jiangsu, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sichuan Provincial People's Hospital,

    RECRUITING

    Chengdu, Sichuan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sun Yat-sen Memorial Hospital

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Hospital of China Medical University

    RECRUITING

    Shenyang, Liaoning, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The second hospital of Lanzhou University

    RECRUITING

    Lanzhou, Gansu, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tianjin Medical University General Hospital

    RECRUITING

    Tianjin, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ying han

    RECRUITING

    Xi'an, Shaanxi, 710032, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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