PRIMARY BILIARY CHOLANGITIS
Clinical trials for PRIMARY BILIARY CHOLANGITIS explained in plain language.
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New combo therapy offers hope for stubborn liver disease
Disease control Recruiting nowThis study tests whether adding fenofibrate to the standard drug ursodeoxycholic acid (UDCA) helps people with primary biliary cholangitis (PBC) who don't respond well to UDCA alone. About 150 adults with PBC will receive either the combination or a placebo for up to 36 weeks. Th…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Xijing Hospital of Digestive Diseases • Aim: Disease control
Last updated May 26, 2026 07:51 UTC
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New drug elafibranor tested in real life for rare liver disease
Disease control Recruiting nowThis study follows about 424 people with primary biliary cholangitis (PBC), a rare liver disease that can lead to scarring and liver failure. Researchers want to see how well the drug elafibranor works and how safe it is when used in everyday medical practice. Participants will b…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Sponsor: Ipsen • Aim: Disease control
Last updated May 26, 2026 07:48 UTC
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New hope for PBC patients: phase 3 trial of CS0159 launches
Disease control Recruiting nowThis study tests a new drug called CS0159 for people with primary biliary cholangitis (PBC), a liver disease, who either didn't get enough help from the standard medicine (UDCA) or couldn't take it. About 135 adults will receive either CS0159 or a placebo, and researchers will ch…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Cascade Pharmaceuticals, Inc • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New combo therapy offers hope for hard-to-treat liver disease patients
Disease control Recruiting nowThis study is for adults with primary biliary cholangitis (a chronic liver disease) who have cirrhosis and did not respond well to the standard drug ursodeoxycholic acid. Researchers want to see if adding fenofibrate to their treatment can improve liver function and reduce sympto…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE2, PHASE3 • Sponsor: Xijing Hospital of Digestive Diseases • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New hope for rare liver disease: seladelpar trial targets cirrhosis complications
Disease control Recruiting nowThis study tests whether the drug seladelpar can help people with primary biliary cholangitis (PBC) who also have cirrhosis. About 318 adults will receive either seladelpar or a placebo. The goal is to see if the drug delays serious liver problems like needing a transplant, devel…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Gilead Sciences • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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New hope for PBC patients: drug targets debilitating itch
Symptom relief Recruiting nowThis study tests an experimental drug called volixibat to see if it can reduce the intense itching caused by primary biliary cholangitis (PBC), a chronic liver disease. About 260 adults with PBC and moderate to severe itching will receive either volixibat or a placebo daily. The …
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE2 • Sponsor: Mirum Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated May 26, 2026 07:26 UTC
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Austrian PBC registry aims to unlock disease mysteries
Knowledge-focused Recruiting nowThis study is creating a registry and optional biobank for 500 adults with primary biliary cholangitis (PBC) in Austria. Researchers will collect medical data and blood samples during regular clinic visits to track how the disease progresses, including complications like liver ci…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Sponsor: Medical University of Vienna • Aim: Knowledge-focused
Last updated May 26, 2026 07:47 UTC
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Can a simple blood test predict liver health in PBC patients?
Knowledge-focused Recruiting nowThis study looks at 3,000 people with primary biliary cholangitis (PBC) to see if changes in a blood marker called alkaline phosphatase after treatment are linked to better survival without serious liver problems. Researchers will track participants over time to build a model tha…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Sponsor: RenJi Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 07:26 UTC