PRIMARY BILIARY CHOLANGITIS
Clinical trials for PRIMARY BILIARY CHOLANGITIS explained in plain language.
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New hope for PBC patients: phase 3 trial of saroglitazar aims to control liver damage
Disease control Not yet recruitingThis study tests a drug called saroglitazar magnesium in about 89 adults with primary biliary cholangitis (PBC) whose liver enzyme levels remain high despite standard treatment or who cannot tolerate it. The goal is to see if the drug can lower alkaline phosphatase, a key marker …
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Zydus Therapeutics Inc. • Aim: Disease control
Last updated May 26, 2026 08:33 UTC
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New hope for PBC patients: drug aims to prevent liver failure and transplant
Disease control Not yet recruitingThis long-term study tests whether the drug saroglitazar magnesium can prevent serious liver complications in people with primary biliary cholangitis (PBC), a chronic liver disease. About 386 adults who are already on standard treatment will receive either the study drug or a pla…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Zydus Therapeutics Inc. • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New hope for PBC itch: experimental drug TH104 enters Mid-Stage trial
Symptom relief Not yet recruitingThis study tests an experimental drug called TH104 for people with primary biliary cholangitis (PBC) who suffer from moderate to severe itching. The trial will include 40 adults aged 18 to 75 and aims to see if the drug is safe and tolerable. Participants will be randomly assigne…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE2 • Sponsor: Tharimmune Inc • Aim: Symptom relief
Last updated May 19, 2026 11:59 UTC
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Spleen scan could spare PBC patients unnecessary scopes
Knowledge-focused Not yet recruitingThis study looks at whether measuring spleen stiffness, along with liver stiffness, can better predict complications in people with Primary Biliary Cholangitis (PBC). About 125 adults with PBC will have regular check-ups including blood tests, ultrasound, and a special scan (Fibr…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: NA • Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated May 26, 2026 08:42 UTC