PRIMARY BILIARY CHOLANGITIS
Clinical trials for PRIMARY BILIARY CHOLANGITIS explained in plain language.
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New hope for PBC: daily pill aims to slow liver damage
Disease control OngoingThis study tests a daily pill called elafibranor in 18 Japanese adults with primary biliary cholangitis (PBC), a rare liver disease that can lead to cirrhosis or transplant. Participants had an inadequate response to standard treatment. The main goal is to see if elafibranor impr…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Ipsen • Aim: Disease control
Last updated May 26, 2026 09:28 UTC
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Liver disease hope: drug combo shows promise in PBC trial
Disease control OngoingThis study tests whether adding fenofibrate to the standard treatment (ursodeoxycholic acid) can improve liver function in people with primary biliary cholangitis (PBC), a chronic liver disease. About 184 adults aged 18-75 with PBC are taking part. The main goal is to see if the …
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE2, PHASE3 • Sponsor: Han Ying • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New hope for liver disease patients who Don't respond to standard treatments
Disease control OngoingThis study tests two doses of a drug called K-808 (pemafibrate) in 46 adults with primary biliary cholangitis, a chronic liver disease. Participants had an inadequate response to standard treatments like ursodeoxycholic acid or obeticholic acid. The main goal is to see if K-808 c…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE2 • Sponsor: Kowa Research Institute, Inc. • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New hope for PBC patients as experimental drug enters long-term safety check
Disease control OngoingThis study is for people with primary biliary cholangitis (PBC) who completed a previous trial of the drug saroglitazar. It aims to see how safe the drug is over a longer period and whether it helps control the disease. About 102 participants will receive the drug and be monitore…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Zydus Therapeutics Inc. • Aim: Disease control
Last updated May 19, 2026 11:59 UTC
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New hope for PBC patients: drug aims to normalize key liver enzyme
Disease control OngoingThis study tests a daily pill called elafibranor in adults with primary biliary cholangitis (PBC) who did not get enough help from standard treatment. The goal is to see if elafibranor can bring a key liver enzyme (ALP) back to normal levels, which may slow liver damage. About 69…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Ipsen • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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New reflex test could spot hidden liver disease in thousands of women
Diagnosis OngoingThis study looks at a simple two-step blood test to find primary biliary cholangitis (PBC) earlier in women aged 40 and older. PBC is a chronic liver disease that often has no symptoms at first, leading to late diagnosis. The test automatically checks for specific antibodies when…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated May 26, 2026 09:31 UTC