New hope for PBC: daily pill aims to slow liver damage
NCT ID NCT06730061
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 24 times
Summary
This study tests a daily pill called elafibranor in 18 Japanese adults with primary biliary cholangitis (PBC), a rare liver disease that can lead to cirrhosis or transplant. Participants had an inadequate response to standard treatment. The main goal is to see if elafibranor improves key liver markers (ALP and bilirubin) over 52 weeks, with follow-up up to 6 years. This is an open-label study, meaning everyone gets the drug, and it focuses on safety and effectiveness.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Chugoku Rosai Hospital
Hiroshima, Japan
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Fukushima Medical University Hospital
Fukushima, Japan
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Hamamatsu University Hospital
Shizuoka, Japan
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Juntendo University Hospital
Tokyo, Japan
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Kagawa University Hospital
Kagawa, Japan
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Kagoshima University Hospital
Kagoshima, Japan
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Nagaoka Red Cross Hospital
Niigata, Japan
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Nara Medical University Hospital
Nara, Japan
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National Hospital Organization Nagasaki Medical Center
Nagasaki, Japan
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National Hospital Organization Osaka National Hospital
Osaka, Japan
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Niigata University Medical & Dental Hospital
Niigata, Japan
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Nippon Medical School - Chiba Hokusoh Hospital
Chiba, Japan
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Shinshu University Hospital
Nagano, Japan
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Teikyo University Hospital
Tokyo, Japan
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Teine Keijinkai Hospital
Hokkaido, Japan
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Tokyo Metropolitan Komagome Hospital
Tokyo, Japan
Conditions
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