New hope for liver disease: drug shows promise in reducing damage
NCT ID NCT06730061
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a daily pill called elafibranor in about 18 Japanese adults with primary biliary cholangitis (PBC), a rare liver disease that can lead to scarring and liver failure. Participants had not responded well to standard treatment. The main goal is to see if the drug improves key liver blood tests (ALP and bilirubin) over 52 weeks, with a possible extension up to 6 years. The study is active but not recruiting.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Chugoku Rosai Hospital
Hiroshima, Japan
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Fukushima Medical University Hospital
Fukushima, Japan
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Hamamatsu University Hospital
Shizuoka, Japan
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Juntendo University Hospital
Tokyo, Japan
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Kagawa University Hospital
Kagawa, Japan
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Kagoshima University Hospital
Kagoshima, Japan
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Nagaoka Red Cross Hospital
Niigata, Japan
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Nara Medical University Hospital
Nara, Japan
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National Hospital Organization Nagasaki Medical Center
Nagasaki, Japan
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National Hospital Organization Osaka National Hospital
Osaka, Japan
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Niigata University Medical & Dental Hospital
Niigata, Japan
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Nippon Medical School - Chiba Hokusoh Hospital
Chiba, Japan
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Shinshu University Hospital
Nagano, Japan
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Teikyo University Hospital
Tokyo, Japan
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Teine Keijinkai Hospital
Hokkaido, Japan
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Tokyo Metropolitan Komagome Hospital
Tokyo, Japan