Ipsen

This study tests a new drug called IPN60300 in adults with advanced solid tumors that have spread or not responded to standard treatments. The goal is to find the safest and most effective dose and to see if the drug can shrink tumors. All participants receive the drug by injecti…

This study tests an experimental pill called IPN01194 in adults with advanced solid tumors (cancers that have spread). The goal is to find the right dose and see if it is safe and can shrink tumors. About 220 people with specific genetic mutations will take the drug by mouth. Thi…

This study tests a new drug called tovorafenib in Japanese children, teens, and young adults with a type of brain tumor called low-grade glioma that has a specific genetic change (BRAF alteration). The main goals are to see if the drug is safe and how the body handles it. Partici…

This study collects information from people with progressive familial intrahepatic cholestasis (PFIC), a rare liver disease that causes severe itching and jaundice, who are taking odevixibat (Bylvay). Researchers will track side effects and long-term outcomes like the need for su…

This study looks at how well the drug cabozantinib works and how safe it is for adults with neuroendocrine tumors (NETs) that have continued to grow despite at least one prior treatment. About 150 participants in Germany and Austria will be followed during their routine care. Doc…

This study tests a new drug called IPN01195 in adults with advanced solid tumors that have spread and no longer respond to standard treatments. The goal is to find a safe dose and see if the drug can shrink tumors. About 85 participants will take the drug by mouth, and researcher…

This study tests a drug called elafibranor in 350 adults with primary sclerosing cholangitis (PSC), a rare disease that scars the bile ducts and can lead to liver failure. Participants will take either elafibranor or a placebo daily for several years to see if the drug delays dis…

This study tests a daily pill called elafibranor in adults with primary biliary cholangitis (PBC) who already have liver scarring (cirrhosis). The goal is to see if the drug can prevent the disease from getting worse, reducing the need for a liver transplant or risk of death. Abo…

This study follows about 424 people with primary biliary cholangitis (PBC), a rare liver disease, who are taking the drug elafibranor. Researchers want to see how well the drug controls the disease and its symptoms over 5 years in everyday medical practice. The goal is to check i…

This study tests a new drug called IPN01203 in about 102 adults with advanced solid tumors that have spread and stopped responding to standard immunotherapy. The goal is to find a safe and effective dose that can slow or stop tumor growth. Participants receive the drug and are mo…

This study follows up to 100 children and adults with fibrodysplasia ossificans progressiva (FOP), an ultra-rare disease where bone grows in places it shouldn't, causing pain and disability. Researchers will collect real-world safety data on those already taking the approved drug…

This study follows 30 people with Alagille syndrome, a rare liver disease that causes severe itching, as they take the drug odevixibat (Bylvay) in their daily lives. Researchers want to see if the medicine helps them avoid surgery or a liver transplant and improves their growth. …

This study tests an injection called IPN10200 to prevent migraines in adults with episodic or chronic migraine. The drug works by blocking pain-causing chemicals in the brain. About 641 participants will receive either the drug or a placebo to find the safest and most effective d…

This study tests a new drug called IPN10200 for adults with cervical dystonia, a condition causing painful neck muscle spasms and stiffness. Current treatments last about 3 months, but IPN10200 is designed to work longer. About 132 participants will receive either the study drug …

This study tests a new drug called IPN10200 for adults with arm muscle stiffness (spasticity) after a stroke or traumatic brain injury. The goal is to find the safest and most effective dose to reduce muscle tightness. About 240 participants will receive either the new drug, a si…

This study tests a single dose of IPN10200, an injectable treatment, to see if it safely reduces moderate to severe frown lines between the eyebrows in adults. Some participants will get the treatment, others a placebo, and later everyone can receive repeat doses. The goal is to …

This study tests a single injection of IPN10200 to improve moderate to severe frown lines between the eyebrows in adults. About 300 participants will receive either the study drug or a placebo. The goal is to see if the treatment safely reduces wrinkle severity and boosts self-co…

This study aims to find how often genetic changes linked to Progressive Familial Intrahepatic Cholestasis (PFIC) occur in adults with unexplained bile flow problems. Researchers will collect health information and blood samples from 150 adults across Spain during a single visit. …

This study follows people of any age who have taken the drug odevixibat while pregnant or breastfeeding. Researchers will collect routine medical data to check for any effects on the mother, developing baby, or infant. No extra tests or visits are required beyond normal care. The…