New registry tracks Odevixibat's Long-Term impact on rare liver disease

NCT ID NCT07185919

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This registry will follow 10 people with progressive familial intrahepatic cholestasis (PFIC) in South Korea who are taking odevixibat (Bylvay). The goal is to see how safe and effective the drug is over the long term in real-world use. Researchers will track side effects and how long patients go without needing surgery or a liver transplant.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

odevixibat (Bylvay)

What this could lead to

If successful, this registry could confirm that odevixibat is safe and effective for long-term use in PFIC patients, supporting its continued use as a treatment option.

What could go wrong

This is a small registry (10 people) in one country, not a controlled trial. It tracks real-world use, so results may not prove cause and effect or apply to all PFIC patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cholestasis, progressive familial intrahepatic 1 progressive familial intrahepatic cholestasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Pusan National University Yangsan Hospital

    RECRUITING

    Gyeongsang, South Korea

  • Seoul National University Hospital

    ACTIVE_NOT_RECRUITING

    Seoul, South Korea

  • Severance Hospital, Yonsei University Health System

    RECRUITING

    Seoul, South Korea