New wrinkle injection shows promise in phase 3 trial

NCT ID NCT07427797

Recruiting now Symptom relief Sponsor: Ipsen Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a single injection of IPN10200, a botulinum toxin type A, to improve moderate to severe frown lines between the eyebrows. About 300 adults will receive either the active drug or a placebo. Researchers will check how well the lines improve over 52 weeks using doctor and patient ratings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

IPN10200 (a botulinum toxin type A injection)

What this could lead to

If it works, this could provide a safe, effective option to temporarily reduce frown lines and improve appearance and confidence.

What could go wrong

This is a cosmetic treatment, not a cure. Results are temporary, and individual responses vary. Possible side effects include injection site reactions or temporary muscle weakness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MODERATE TO SEVERE GLABELLAR LINES

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Ablon Skin Institute and Research Center
RECRUITING

Manhattan Beach, California, 90266, United States
Advanced Research Associates
RECRUITING

Glendale, Arizona, 85308, United States
Art of Skin MD
RECRUITING

Solana Beach, California, 92075, United States
Ava T. Shamban, M.D., Inc.
RECRUITING

Santa Monica, California, 90404, United States
Avacare
NOT_YET_RECRUITING

Scottsdale, Arizona, 85260, United States
Bertucci MedSpa
NOT_YET_RECRUITING

Woodbridge, Ontario, L4L 8E2, Canada
Carruthers and Humphrey Cosmetic Medicine
RECRUITING

Vancouver, British Columbia, V5Z 4E1, Canada
Centre de Recherche Dermatologique de Quebec
NOT_YET_RECRUITING

Québec, Quebec, G1V4X7, Canada
Clinical Research Center of the Carolinas
NOT_YET_RECRUITING

Charleston, South Carolina, 29407, United States
Dermatology and Laser Surgery Center
RECRUITING

Houston, Texas, 77004, United States
ICON Dermatology and Aesthetics
RECRUITING

Bethesda, Maryland, 20852, United States
Institute of Cosmetic and Laser Surgery
RECRUITING

Oakville, Ontario, L6J 7W5, Canada
Investigate MD, LLC
RECRUITING

Scottsdale, Arizona, 85260, United States
Keith A. Marcus, MD Inc
RECRUITING

Redondo Beach, California, 90277, United States
Pacific Clinical Innovations Inc.
RECRUITING

Vista, California, 92083, United States
Pacific Dermaesthetics Inc.
NOT_YET_RECRUITING

Vancouver, British Columbia, V6H4E1, Canada
Pflugerville Dermatology Clinical Research Center, Inc. d/b/a Austin Institute for Clinical Research
RECRUITING

Pflugerville, Texas, 78660, United States
Skin Research Institute
RECRUITING

Coral Gables, Florida, 33146, United States
Skin Wellness Dermatology - Homewood
RECRUITING

Birmingham, Alabama, 35209, United States
SkinDC
RECRUITING

Arlington, Virginia, 22209, United States
Sweat clinics of canada
RECRUITING

Toronto, Ontario, M5R 3N8, Canada
West Dermatology
NOT_YET_RECRUITING

San Diego, California, 92121, United States
Westlake Dermatology & Cosmetic Surgery - Westlake
RECRUITING

Austin, Texas, 78746-5059, United States