New wrinkle treatment eveotox takes on botox in major trial

NCT ID NCT06937944

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This phase 3 study tests a new injection called Eveotox, made from a lab-grown version of botulinum toxin, against Botox and a placebo for moderate to severe frown lines. About 669 adults aged 18 to 65 will receive one or more treatments. Researchers will check how well it smooths wrinkles and monitor for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

recombinant botulinum toxin type A (Eveotox)

What this could lead to

If it works, this could offer a new, effective option for temporarily reducing frown lines between the eyebrows.

What could go wrong

This is a cosmetic treatment, not a cure. Results are temporary, and side effects like bruising or drooping eyelids are possible. It may not work as well as Botox.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University

    RECRUITING

    Hangzhou, Zhejiang, China

  • Huashan Hospital, Fudan University

    RECRUITING

    Shanghai, Shanghai Municipality, China

  • Peking Union Medical College Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

  • Peking University First Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

  • Peking University Third Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

  • The Affiliated Hospital of Xuzhou Medical University

    RECRUITING

    Xuzhou, Jiangsu, China

  • The First Affiliated Hospital of Chongqing Medical University

    RECRUITING

    Chongqing, Chongqing Municipality, China

  • The First Affiliated Hospital of Jinan University

    RECRUITING

    Guangzhou, Guangdong, China

  • The First Hospital of Hebei Medical University

    RECRUITING

    Shijiazhuang, Hebei, China

  • The Third Affiliated Hospital of Sun Yat-sen University

    RECRUITING

    Guangzhou, Guangdong, China

  • The Third Xiangya Hospital of Central South University

    RECRUITING

    Changsha, Hunan, China

  • Tianjin Medical University General Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, China

  • West China Hospital, Sichuan University

    RECRUITING

    Chengdu, Sichuan, China

  • Xianyang Hospital of Yan'an University

    RECRUITING

    Xianyang, Shanxi, China

  • Zhejiang Provincial People's Hospital

    RECRUITING

    Hangzhou, Zhejiang, China