New Botox-Like injection aims to smooth frown lines safely
NCT ID NCT06583486
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study tests a new form of botulinum toxin (YY001) for treating moderate to severe frown lines between the eyebrows. About 488 adults aged 18 to 65 will receive repeated injections over time. Researchers will monitor safety, side effects, and how well the treatment works to reduce wrinkle severity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
recombinant botulinum toxin type A (YY001)
What this could lead to
If successful, this could provide a safe and effective option for reducing frown lines with repeated treatments.
What could go wrong
This is a cosmetic treatment, not a cure for any disease. Side effects may include injection site reactions or temporary muscle weakness.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MODERATE TO SEVERE GLABELLAR LINES are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine
Hangzhou, Zhejiang, China
-
Beijing Tsinghua Changgung Hospital
Beijing, China
-
Guangdong Second People's Hospital
Guangzhou, Guangdong, China
-
Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, China
-
Peking Union Medical College Hospital , Chinese Academy of Medical Sciences
Beijing, China
-
Peking University First Hospital
Beijing, China
-
Peking University Third Hospital
Beijing, China
-
Plastic Surgery Hospital, Chinese Academy of Medical Science
Beijing, China
-
The First Affiliated Hospital of Chongqing Medical University
Hongqing, China
-
The Second Affiliated Hospital Of Xi'an Jiaotong University
Xian, Shanxi, China
-
The Third Affiliated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, China
-
The Third Xiangya Hospital of Central South University
Changsha, Hunan, China
-
Tianjin Medical University General Hospital
Tianjin, China
-
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China
-
West China School of Medicine/West China Hospital of Sichuan University
Chengdu, Sichuan, China
-
Zhejiang Provincial People's Hospital
Hangzhou, Zhejiang, China