New Botox-Like injection aims to smooth frown lines safely
NCT ID NCT06583486
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study tests a new form of botulinum toxin (YY001) for treating moderate to severe frown lines between the eyebrows. About 488 adults aged 18 to 65 will receive repeated injections over time. Researchers will monitor safety, side effects, and how well the treatment works to reduce wrinkle severity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- recombinant botulinum toxin type A (YY001)
- What this could lead to
- If successful, this could provide a safe and effective option for reducing frown lines with repeated treatments.
- What could go wrong
- This is a cosmetic treatment, not a cure for any disease. Side effects may include injection site reactions or temporary muscle weakness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine
Hangzhou, Zhejiang, China
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Beijing Tsinghua Changgung Hospital
Beijing, China
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Guangdong Second People's Hospital
Guangzhou, Guangdong, China
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Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, China
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Peking Union Medical College Hospital , Chinese Academy of Medical Sciences
Beijing, China
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Peking University First Hospital
Beijing, China
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Peking University Third Hospital
Beijing, China
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Plastic Surgery Hospital, Chinese Academy of Medical Science
Beijing, China
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The First Affiliated Hospital of Chongqing Medical University
Hongqing, China
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The Second Affiliated Hospital Of Xi'an Jiaotong University
Xian, Shanxi, China
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The Third Affiliated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, China
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The Third Xiangya Hospital of Central South University
Changsha, Hunan, China
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Tianjin Medical University General Hospital
Tianjin, China
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China
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West China School of Medicine/West China Hospital of Sichuan University
Chengdu, Sichuan, China
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Zhejiang Provincial People's Hospital
Hangzhou, Zhejiang, China
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