New wrinkle treatment AGN-151586 tested in japanese adults
NCT ID NCT06151561
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tested an investigational botulinum toxin injection called AGN-151586 for moderate to severe frown lines (glabellar lines) in 24 Japanese adults. Participants received either the active drug or a placebo, and researchers measured wrinkle improvement and safety over about 6 weeks. The goal is to see if this treatment is safe and effective for this population.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
AGN-151586 (botulinum toxin injection)
What this could lead to
If it works, this could offer a safe and effective option for reducing frown lines in Japanese adults.
What could go wrong
This is a very early, small Phase 1/2 trial with only 24 participants. The results may not apply to everyone, and side effects or lack of effect are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Tokyo Center Clinic /ID# 257898
Central District, Tokyo, 103-0028, Japan