Ipsen

This study is testing a drug called elafibranor in adults with primary sclerosing cholangitis (PSC), a rare disease that scars and blocks the liver's bile ducts. The main goal is to check the drug's safety and side effects. Researchers will also measure if it improves key liver b…

This study is testing if adding a daily pill called cabozantinib to standard supportive care helps control osteosarcoma (a type of bone cancer) for longer in children and young adults whose cancer cannot be fully removed by surgery. Participants, aged 5 to 30, will be randomly as…

This study is testing whether a daily pill called elafibranor can help control primary biliary cholangitis (PBC), a rare liver disease that damages bile ducts. It will involve about 18 Japanese adults whose current treatment isn't working well enough. Researchers will check if th…

This study is testing whether regular injections of Dysport, a medication similar to Botox, can safely reduce the number of migraine days for adults with chronic migraines. About 759 participants will receive either Dysport or a placebo shot in their head, neck, and shoulders ove…

This study observes how patients with advanced kidney cancer respond to cabozantinib treatment in real-world Belgian clinics. Researchers will track 150 patients receiving this medication alone or combined with nivolumab to understand how treatment is managed in everyday practice…

This study is testing if a medication called Dysport, which is similar to Botox, can help prevent migraine headaches in adults. About 750 people with frequent episodic migraines will receive injections in their head, neck, and shoulders to see if it reduces their number of migrai…

This study is testing whether a drug called elafibranor can help control primary biliary cholangitis (PBC), a serious liver disease. It's for adults whose current treatment isn't working well or who can't tolerate it. Researchers will compare elafibranor against a placebo to see …

This study is testing a drug called elafibranor for adults with primary biliary cholangitis (PBC), a serious liver disease, who don't get enough benefit from the standard medication. The main goal is to see if the drug improves key liver blood tests and reduces symptoms like seve…

This study is observing how well the combination of cabozantinib and nivolumab works for adults with advanced kidney cancer in real-world medical settings. Researchers are following 311 patients who have already been prescribed this two-drug treatment as their first therapy. The …

This study is observing how a standard treatment for stiff, tight arm muscles (spasticity) affects the daily lives of patients and their caregivers. It will follow 113 adults with arm stiffness caused by a past brain or spinal cord injury who are receiving routine injections of a…

This study aims to understand how standard hormone-blocking treatments affect the quality of life of premenopausal women with early-stage breast cancer. Researchers will follow 450 women in Italy who are already receiving these treatments, tracking their well-being, hormone level…

This study is observing how patients with advanced kidney cancer respond to treatment with the drug cabozantinib, either alone or combined with nivolumab, in everyday clinical practice. It involves 224 adults who are already receiving this as their first treatment. The main goal …

This study aims to better understand two common and disruptive symptoms of Primary Biliary Cholangitis (PBC): itching and poor sleep. Researchers will use a special wrist-worn sensor called ADAM to automatically measure how often and how intensely 30 participants scratch in their…