Ipsen

This study tests a new oral drug called IPN01194 in 36 adults with advanced solid tumours (melanoma, colorectal, pancreatic, or head and neck cancer) that have not responded to standard treatments. The goal is to find the right dose and check if it is safe, while also looking for…

This study tests a drug called elafibranor in 68 adults with primary sclerosing cholangitis (PSC), a rare liver disease that damages bile ducts. The main goal is to check the drug's safety and side effects compared to a placebo. Researchers will also look at blood tests to see if…

This study tests a new drug called elafibranor in people with primary biliary cholangitis (PBC), a rare liver disease that can lead to scarring and liver failure. Participants either did not get enough help from or could not take the standard medicine. The goal is to see if elafi…

This study tests a daily pill called elafibranor in about 18 Japanese adults with primary biliary cholangitis (PBC), a rare liver disease that can lead to scarring and liver failure. Participants had not responded well to standard treatment. The main goal is to see if the drug im…

This study tests whether elafibranor, a daily pill, can normalize alkaline phosphatase (ALP) levels in adults with primary biliary cholangitis (PBC) who did not respond well to or cannot take standard treatment. About 69 participants will receive either elafibranor or a placebo f…

This study tests whether Dysport injections can prevent chronic migraines in adults. Chronic migraine means having at least 15 headache days per month, with 8 being migraines. Participants receive injections into head, neck, and shoulder muscles every 12 weeks for up to 60 weeks.…

This study looks at how well the drug tazemetostat works in adults with a slow-growing blood cancer called follicular lymphoma that has returned or not responded after at least two prior treatments. Participants take tazemetostat as prescribed by their doctor in normal medical pr…

This phase 3 study tests whether Dysport (a botulinum toxin type A) injections can prevent episodic migraine in adults. About 751 participants receive either Dysport or placebo injections every 12 weeks for up to 36 weeks. The goal is to see if the treatment reduces the number of…

This study tests a new injection called IPN10200 for moderate to severe upper facial lines, like frown lines and forehead wrinkles. About 727 adults aged 18 to 65 will receive either the injection or a placebo. The goal is to see if it safely reduces wrinkles better than a dummy …

This study tracks how 150 patients in Belgium use the drug cabozantinib (Cabometyx), alone or with nivolumab, for advanced or metastatic kidney cancer. It looks at real-world dosing, treatment changes, and quality of life. The goal is to understand how these treatments are actual…

This study observes 224 adults with advanced or metastatic kidney cancer who are taking cabozantinib alone or with nivolumab as their first treatment. Researchers track how often doses are reduced, paused, or stopped due to side effects in everyday medical practice. The goal is t…

This study follows 450 premenopausal women with early-stage hormone-positive breast cancer in Italy. Researchers want to see how adding triptorelin to standard hormone therapy affects quality of life and hormone levels. The goal is to better understand the real-world impact of tr…

This study looks at a rare liver disease called PFIC, which causes severe itching and liver damage. Researchers compare patients who took the drug odevixibat to those who did not, using data from past studies and a patient registry. The goal is to see if odevixibat helps avoid li…

This study follows 113 adults with arm stiffness from brain injuries who are receiving botulinum toxin injections in routine care. Researchers measure how the treatment affects the burden on caregivers, the patient's disability, and other health factors over time. The goal is to …

This study follows over 1,000 adults who had their first stroke to see how many develop spasticity—a condition where muscles become stiff or rigid—within the first year. Researchers will monitor participants and create a best-practice guide for doctors to spot and treat this comm…