New study aims to predict who gets muscle stiffness after stroke

NCT ID NCT06055725

Ongoing Knowledge-focused Sponsor: Ipsen Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows over 1,000 adults who had their first stroke to see how many develop spasticity—a condition where muscles become stiff or rigid—within the first year. Researchers will monitor participants and create a best-practice guide for doctors to spot and treat this common complication. The goal is to improve care and quality of life for stroke survivors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could establish a standard guideline for monitoring post-stroke spasticity, helping doctors identify patients who need treatment earlier.

What could go wrong

This is an observational study, not testing a new treatment. It may not change outcomes directly, and results might not apply to all stroke patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SPASTICITY AS SEQUELA OF STROKE

Contacts and locations

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Locations

AOU San giovanni di Dio e Ruggi d'aragona Univ. di Salerno

Salerno, 84131, Italy
AOU maggiore della Carita'

Novara, 28100, Italy
Angelholm Northern Hospital

Ängelholm, 26281, Sweden
Azienda Ospedaliero Universitaria OO RR di Foggia

Foggia, 71100, Italy
CHU Bordeaux-Hopital Pellegrin

Bordeaux, 33076, France
CHU Nantes

Saint-Jacques, France
CHU de Caen

Caen, 14033, France
CHU de Rennes, Hopital de Pontchaillou

Rennes, 35033, France
Charité - Universitaetsmedizin Berlin - Campus Charite Mitte (CCM)

Berlin, 10117, Germany
Complexo Hospitalario Universitario De Vigo - Hospital Do Mexoeiro

Vigo, 36200, Spain
Dayton Center for Neurological Disorders

Centerville, Ohio, 45459, United States
Duke University School of Medicine

Durham, North Carolina, 27705, United States
Heinrich-Heine-Universitaet Duesseldorf - Universitaetsklinikum Duesseldorf (UKD)

Düsseldorf, Germany
Hospices Civils de Lyon (HCL) - Hopital Henry Gabrielle

Saint-Genis-Laval, 69230, France
Hospital Clinic i Provincial

Barcelona, Spain
Hospital Mutua De Terrassa

Barcelona, 08221, Spain
Hospital Universitari Germans Trias i Pujol (HUGTP)

Badalona, Spain
Hospital Universitario La Paz

Madrid, 28046, Spain
Hospital Universitario Miguel Servet de Zaragoza

Zaragoza, Spain
Hospital Universitario Virgen del Rocio

Seville, 41013, Spain
Karnsjukhuset Skaraborg

Skövde, 54185, Sweden
Kings College Hospital NHS Foundation Trust

London, United Kingdom
Klinikum Altenburger Land GmbH

Altenburg, Germany
Knight Neurology

Rockledge, Florida, 32955, United States
Loma Linda

Anderson, California, 92354, United States
Madonna Rehabilitation Hospital - Omaha Campus

Omaha, Nebraska, 68118, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
McGovern Medical School - UT Physicians - Neurology (Adult Neurology Clinic) - Texas Medical Center Location

Houston, Texas, 77030, United States
Medical College of Wisconsin

Milwauke, Wisconsin, 53226, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Medstar Health Research Institute, Inc

Hyattsville, Maryland, 20782, United States
Methodist Physicians Clinic

Omaha, Nebraska, 68114, United States
Milan University, Humanitas Clinical Institute

Milan, Italy
Moss Rehab

Elkins Park, Pennsylvania, 19027, United States
Neurological Rehabilitation Unit- Policlinico Borgo Roma.

Verona, 37134, Italy
Neuromotor And Cognitive Rehabilitation Research Centre; Dep. Of Neurological, Neuropsychological, Morphological And Movement Sciences; Univ. Of Verona - Neurological Rehabilitation Unit- Policlinico Borgo Roma

Verona, Italy
Nottingham University Hospitals NHS Trust - Nottingham City Hospital

Nottingham, United Kingdom
Ospedal Valduce

Lecco, 23845, Italy
Skane University Hospital

Malmö, 20502, Sweden
Sodra Alvsborgs Sjukhus

Borås, 50455, Sweden
South Tees Hospitals Foundation Nhs Trust

Middlesbrough, United Kingdom
Spaulding Rehabilitation Hospital

Boston, Massachusetts, 02129, United States
The University Of Texas Southwestern Medical Center

Dallas, Texas, 75390-8869, United States
The Walton Centre

Liverpool, United Kingdom
Universidad Autonoma de Madrid (UAM) - Hospital Universitario de La Princesa

Madrid, Spain
Universitaetsklinikum Essen

Essen, 45147, Germany
Universitaetsklinikum Schleswig-Holstein Campus Luebeck

Lübeck, 23562, Germany
Universitaetsklinikum Schleswig-Holstein, UKSH-Campus Kiel

Kiel, 24105, Germany
Universitaetsklinikum Tuebingen (UKT)

Tübingen, Germany
Universitaetsmedizin der Johannes - Gutenberg Universitaet Mainz

Mainz, 55131, Germany
University Hospital Carl Gustav Carus

Dresden, Germany
University Hospitals of Leicester NHS Trust - Leicester General Hospital (LGH)

Leicester, LE5 4PW, United Kingdom
University Of Utah

Salt Lake City, Utah, 84112, United States
University of Missouri Health Care

Columbia, Missouri, 65212, United States