PRIMARY BILIARY CHOLANGITIS
Clinical trials for PRIMARY BILIARY CHOLANGITIS explained in plain language.
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New hope for PBC patients: experimental drug CNP-104 tested in clinical trial
Disease control CompletedThis study tested a new medicine called CNP-104 in 42 adults aged 18-75 with primary biliary cholangitis (PBC), a liver disease that didn't improve with standard treatments. The goal was to check if CNP-104 is safe and how it affects the body. Participants received either the dru…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE1, PHASE2 • Sponsor: COUR Pharmaceutical Development Company, Inc. • Aim: Disease control
Last updated May 26, 2026 09:37 UTC
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New combo therapy shows promise for rare liver disease
Disease control CompletedThis study tested whether adding the drug bezafibrate to another drug, obeticholic acid, helps people with primary biliary cholangitis (PBC), a chronic liver disease. 72 adults with PBC took one or both drugs for 12 weeks. The main goal was to see if the combination improved live…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE2 • Sponsor: Intercept Pharmaceuticals • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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New liver drug shows promise in PBC trial
Disease control CompletedThis study tested a drug called saroglitazar magnesium in 196 adults with primary biliary cholangitis (PBC), a chronic liver disease. Participants either took the drug or a placebo pill to see if it improved liver function markers. The goal was to find a new treatment option for …
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE2, PHASE3 • Sponsor: Zydus Therapeutics Inc. • Aim: Disease control
Last updated May 20, 2026 11:54 UTC
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Online wellness program shows promise for easing mental distress in chronic illness
Symptom relief CompletedThis study tested a 12-week online program that combines gentle movement, breathing exercises, and coping skills for adults with chronic conditions like heart failure, liver disease, or cancer. The goal was to see if it could reduce anxiety and depression. Over 800 people took pa…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated May 26, 2026 09:30 UTC
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Wearable device tracks itch and sleep in rare liver disease
Knowledge-focused CompletedThis study used a small wearable device called the ADAM sensor to track scratching and sleep patterns in 30 adults with primary biliary cholangitis (PBC), a rare liver disease that often causes severe itching and poor sleep. Participants wore the sensor for 7 nights at a time ove…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Sponsor: Ipsen • Aim: Knowledge-focused
Last updated May 26, 2026 09:40 UTC
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Liver study measures drug levels in PBC patients
Knowledge-focused CompletedThis study looked at how the body handles the drug seladelpar in 24 adults with primary biliary cholangitis (PBC) and varying degrees of liver impairment. Researchers measured drug levels in the blood and urine to see how liver function affects the drug's breakdown. The goal was …
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE1 • Sponsor: Gilead Sciences • Aim: Knowledge-focused
Last updated May 26, 2026 09:31 UTC