New hope for PBC patients: experimental drug CNP-104 tested in clinical trial
NCT ID NCT05104853
First seen Mar 12, 2026 · Last updated May 22, 2026 · Updated 11 times
Summary
This study tested a new medicine called CNP-104 in 42 adults aged 18-75 with primary biliary cholangitis (PBC), a liver disease that didn't improve with standard treatments. The goal was to check if CNP-104 is safe and how it affects the body. Participants received either the drug or a placebo, and were followed for up to 2 years to monitor side effects and changes in liver health.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cleveland Clinic - Florida
Weston, Florida, 33331, United States
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Digestive Healthcare of Georgia
Atlanta, Georgia, 30309, United States
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Florida Research Institute
Lakewood Rch, Florida, 34211-4930, United States
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GI PROS Research
Naples, Florida, 34102, United States
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Henry Ford Health System
Novi, Michigan, 48377, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Mayo Clinic Florida
Jacksonville, Florida, 32224, United States
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Montefiore Medical Center
The Bronx, New York, 10467, United States
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OM Research
Lancaster, California, 93534, United States
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Peak Gastroenterology Associates
Colorado Springs, Colorado, 80907, United States
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Southern California Research Center
Coronado, California, 92118, United States
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Texas Liver Institute
San Antonio, Texas, 78215, United States
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University of California Davis Health
Sacramento, California, 95817, United States
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University of Chicago Medical Center
Chicago, Illinois, 60637, United States
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University of Florida - Hepatology Research
Gainesville, Florida, 32610, United States
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University of Virginia
Charlottesville, Virginia, 22903, United States
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Washington University School of Medicine in St. Louis
St Louis, Missouri, 63110, United States
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Yale School of Medicine
New Haven, Connecticut, 06520, United States
Conditions
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