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Liver disease hope: drug combo shows promise in PBC trial

NCT ID NCT06174402

First seen Jan 11, 2026 · Last updated May 20, 2026 · Updated 13 times

Summary

This study tests whether adding fenofibrate to the standard treatment (ursodeoxycholic acid) can improve liver function in people with primary biliary cholangitis (PBC), a chronic liver disease. About 184 adults aged 18-75 with PBC are taking part. The main goal is to see if the combination helps normalize a key liver enzyme (alkaline phosphatase) and reduces itching.

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Contacts and locations

Locations

  • Jiangsu Province Hospital

    Nanjing, Jiangsu, China

  • Nanjing Drum Tower Hospital

    Nanjing, Jiangsu, China

  • Nanjing Second Hospital

    Nanjing, Jiangsu, China

  • Peking Union Medical College Hospital

    Beijing, China

  • Shengjing Hospital Affiliated to China Medical University

    Shenyang, Liaoning, China

  • Sun Yat-sen Memorial Hospital

    Guangzhou, Guangdong, China

  • The Second Affiliated Hospital of Kunming Medical University

    Kunming, Yunnan, China

  • The second hospital of Lanzhou University

    Lanzhou, Gansu, China

  • Xijing Hospital

    Xi'an, Shaanxi, China

  • Yan'an University Affiliated Hospital

    Yan’an, Shanxxi, China

Conditions

Explore the condition pages connected to this study.