University Of Toronto

This study tests whether a digital diet program, combined with extra vegetables and soy foods, can lower blood pressure in adults with hypertension, obesity, and type 2 diabetes. 300 participants will be split into three groups: one gets highly processed soy foods, another gets m…

This study looks at whether exercise and a healthy diet can reduce the risk of heart problems and diabetes in women who have had breast cancer. About 45 postmenopausal survivors will be placed into one of three groups: exercise only, exercise plus diet counseling, or a stretching…

This study looks at whether eating all your food within a specific 9-hour window each day (time-restricted eating) can improve blood sugar control in people with obesity who have or are at risk for type 2 diabetes. Researchers will compare three different eating windows to see if…

This study looks at whether a 16-week cardiac rehabilitation exercise program can improve heart health in women who have had early-stage breast cancer. About 100 participants will take part in the program, and their fitness, heart function, and quality of life will be measured be…

This study tests whether a digital heart health program (app and online sessions) added to usual care can lower cholesterol and reduce heart attacks, strokes, and other major heart events over 7 years. About 1,100 adults with heart disease or high risk factors who are already on …

This study tests whether adding the HIV drug efavirenz to a person's regular antiretroviral therapy (ART) can kill cells that still harbor HIV, even when the virus is well-controlled. About 26 adults with HIV who have very low but detectable virus levels despite good medication a…

This study looks at how exercise and diet affect heart health in women with metabolic risks. Researchers will compare exercise alone, exercise plus diet counseling, and stretching in 180 pre- and postmenopausal women over 6 months. The goal is to see which approach best reduces i…

This study looks at whether eating three servings of dairy each day (milk, yogurt, cheese) can improve body weight, body composition, and blood sugar in overweight adolescents (ages 15-18) and older adults (ages 60-80). Over six months, participants are randomly assigned to eithe…

This study tests an online program called SCI&U that pairs people with spinal cord injury (SCI) with trained peer health coaches. The goal is to help participants manage their health, feel less distressed, and gain confidence after leaving the hospital. About 76 adults in British…

This study looks at whether taking short walks after meals or doing quick 'activity snacks' can help breast cancer survivors control their blood sugar better than a standard 30-minute walk. The researchers will compare these strategies in 24 women who have had breast cancer and a…

This study tests whether adding motivational counseling to a virtual exercise program helps cancer survivors stay active. About 236 people who finished cancer treatment within the last 5 years will join a 6-month program with supervised exercise and either standard or enhanced co…

This study looks at 50 people having knee replacement revision surgery. It compares two groups: one gets spinal morphine for pain, the other does not. The goal is to see if skipping morphine lowers the chance of needing a catheter for urine retention, while still keeping pain und…

This study looks at whether different types of exercise can help women in perimenopause manage symptoms like hot flashes and night sweats. Researchers will compare following standard activity guidelines, doing high-intensity interval training (HIIT), or just stretching. The main …

This study tests a 6-week group therapy program for adults with psychosis. The therapy focuses on changing negative core beliefs, which are thought to drive symptoms. Researchers want to see if the program is safe, feasible, and can improve beliefs and symptoms. All 38 participan…

This study checks if a non-invasive breath test can measure how well protein builds muscle as accurately as the current gold-standard method, which requires muscle biopsies. Eight healthy adults aged 18-35 will consume a special tracer and provide breath, urine, and blood samples…

This study compares two rehabilitation approaches to improve finger movement in 40 people who had a stroke 6 months to 2 years ago. One method encourages using any strategy to reach goals, while the other focuses on improving movement technique. Participants will do 10 days of pi…

This study looks at how natural menstrual cycles and birth control pills change the way women build muscle after weightlifting. Researchers will measure muscle protein synthesis in 20 active women aged 18-40. The goal is to provide better training and nutrition advice for women.

This study looks at how a common breast cancer treatment called aromatase inhibitors affects the heart and blood vessels during the first 6 months of use. Researchers will compare 40 women with breast cancer to similar women without cancer. The goal is to understand early changes…

This study looks at how fast the body turns EPA (an omega-3 fat) into DHA (another omega-3) in healthy people. Researchers want to know if a person's sex and a specific gene affect this process. 64 healthy adults will take EPA supplements for 12 weeks and give blood samples. The …

This study looks at whether the phase of your menstrual cycle (follicular vs. luteal) changes how your body responds to sprint interval training. Researchers will measure endurance performance and muscle changes in 24 healthy women over 2 weeks. The goal is to understand if timin…