University Of Pittsburgh
Clinical trials sponsored by University Of Pittsburgh, explained in plain language.
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Lifestyle coaching may ward off depression in older widows and widowers
Prevention CompletedThis study tested whether a 12-week healthy lifestyle program could prevent major depression in older adults who recently lost a spouse. 151 people aged 60+ who were at high risk for depression took part. Half received coaching on sleep, meals, and physical activity, while the ot…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Prevention
Last updated May 01, 2026 15:59 UTC
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New telehealth program aims to sharpen memory in young cancer survivors
Symptom relief CompletedThis study tested a telehealth program called MAAT-YS for young adults (ages 18-39) who had cancer as children and now have memory or attention problems. Seven participants completed 8 weekly video sessions with a workbook and homework. The goal was to see if the program could im…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated May 01, 2026 15:59 UTC
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New online program aims to boost energy in breast cancer survivors
Symptom relief CompletedThis study tested a program called Maximizing Energy to help women who finished breast cancer treatment manage their fatigue. Fifteen women took part, and researchers checked if the program was easy to follow and if it reduced tiredness compared to a general health education prog…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated May 01, 2026 15:57 UTC
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Does washing fat before injecting it into your face make a difference?
Symptom relief CompletedThis study looked at whether washing fat with saline before injecting it into the face improves skin appearance more than using unwashed fat. Twenty-six healthy women aged 35 to 70 received fat from their own body into both sides of their face. Researchers measured changes in wri…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Apr 29, 2026 15:04 UTC
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Fitbits and phone alerts cut hospital returns after bladder surgery?
Symptom relief CompletedThis study tested whether using wearable activity trackers (Fitbits) and daily smartphone check-ins could help people recover better after bladder cancer surgery. About 38 patients took part, with some getting the remote monitoring and alerts to their care team if problems were d…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Apr 28, 2026 13:02 UTC
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Can TikTok and YouTube help LGBTQ+ youth find mental health help?
Knowledge-focused CompletedThis study tested whether using online tools like YouTube, TikTok, and resource links can help sexual and gender minority youth (ages 14-19) seek help for depression and anxiety. 81 teens joined a private Discord group for 4 weeks, with different groups getting different combinat…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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Can simple checklists curb opioid misuse? new study tests doctor-friendly guides
Knowledge-focused CompletedThis study tested whether doctors in primary care clinics would use simple decision guides (algorithms) to help patients with chronic pain who misuse opioids. 49 clinicians participated over 6-9 months. The goal was to see if the guides were easy to use and acceptable, not to dir…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated May 01, 2026 16:00 UTC
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Brain wave test may spot depression risk in teens
Knowledge-focused CompletedThis study looked at whether brain wave patterns (EEG) can help predict which teenage girls are at higher risk for depression. Researchers measured how much attention girls paid to negative images versus task-related images. They also tested if real-time neurofeedback could shift…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated May 01, 2026 16:00 UTC
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Lung transplant infection study reveals hidden risks
Knowledge-focused CompletedThis study followed 600 lung transplant patients to see how common viral and bacterial infections are after surgery and how they affect long-term health. Researchers focused on a germ called C. pneumoniae and its link to a serious lung condition called bronchiolitis obliterans. T…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated May 01, 2026 15:59 UTC
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Chemo's genetic impact on sperm revealed in new study
Knowledge-focused CompletedThis study looked at how chemotherapy changes the DNA in sperm of men with cancer. Researchers collected semen samples before and after the first round of chemo to compare genetic differences. The goal was to understand short-term effects on sperm health and DNA, not to treat the…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated May 01, 2026 15:58 UTC
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Which advance care plan works best for cancer patients?
Knowledge-focused CompletedThis study looked at two ways to help people with advanced cancer plan their future medical care: meeting with a trained guide in person or using a website. About 672 patients took part to see which method helps them talk about and record their wishes more clearly. The goal is to…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC
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Brain study reveals secrets of speech flexibility
Knowledge-focused CompletedThis study looked at how the brain's temporal lobe processes speech sounds in 48 epilepsy patients who already had electrodes implanted for medical reasons. Researchers measured brain activity while participants listened to speech sounds with varying features like voice timing an…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC
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Wellness programs for disabilities: do they deliver better health at lower cost?
Knowledge-focused CompletedThis study looked at whether community-based wellness programs can improve health, quality of life, and care experience while reducing costs for adults with disabilities like spina bifida, cerebral palsy, spinal cord injury, or traumatic brain injury. Researchers enrolled 130 par…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated May 01, 2026 15:56 UTC
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Smart alerts aim to shield kidneys from drug harm in hospitals
Knowledge-focused CompletedThis study tested a computer system that alerts pharmacists when a hospitalized patient is at high risk for kidney injury caused by medications. The pharmacist then works with the patient's doctor to adjust care. The goal was to see if this approach reduces serious kidney complic…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:14 UTC
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Brain scans in newborns may predict future development
Knowledge-focused CompletedThis study looked at 557 newborns with brain injuries to see if advanced MRI scans can predict how they will develop as they grow. Researchers compared brain images with later tests of thinking and behavior. The goal is to help doctors find and treat brain injuries earlier.
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:03 UTC
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Teens' past stress may hinder depression coping skills, study finds
Knowledge-focused CompletedThis study looked at how stressful life events affect the ability of teens aged 12-15 with depression to learn a coping skill called cognitive restructuring. Researchers taught the skill and then tested how well teens learned and remembered it over six months. The goal was to und…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:01 UTC
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Balance breakthrough: study reveals key factors in dizziness recovery
Knowledge-focused CompletedThis study looked at how physical impairments and personal factors (like age or mindset) affect daily activities and participation in people with dizziness and balance problems. Researchers measured these factors before and after a balance therapy program in 52 adults. The goal w…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:01 UTC