University Of Pittsburgh

This pilot study will test whether a multi-domain program—including psychological support, diet changes, targeted therapy, and parent counseling—can improve thinking skills and behavior in 50 children (ages 6-16) with Type-1 diabetes who have hypoglycemia unawareness (not feeling…

This study tests a gum surgery for adults with receding gums on the tongue side of their lower teeth. The surgery uses a tissue graft from the roof of the mouth to cover exposed roots. Twenty participants will be followed for up to 24 months to see how much root is covered and ho…

This study tests whether using a person's genetic information to guide medication decisions can improve depression symptoms. About 220 adults starting or changing antidepressants will be randomly assigned to receive either pharmacist-led medication management with genetic test re…

This study tests whether placing a thin layer of the patient's own fat under a skin graft on the penis leads to better healing, feel, and function. Twenty-four men scheduled for reconstructive penile surgery will be randomly assigned to receive either the standard skin graft alon…

This study tests whether prucalopride, a drug used for gut issues, can improve thinking and memory in people with schizophrenia. About 34 adults will take the drug for 4 weeks while staying on their usual medications. Researchers will measure changes in memory, attention, and pro…

This study will create a computer tool to predict which older adults are at high risk for serious problems after heart or blood vessel surgery. It will also test if special programs before and during surgery can help prevent confusion, heart issues, and death. About 1,200 people …

This study looks at 24 kidney transplant patients to understand why some rejections come back or don't go away. Researchers will examine tiny pieces of the kidney (biopsies) and blood samples to see which cells and genes are involved. The goal is to find patterns that could help …