University Of Pittsburgh

This study tests a new program where schools, families, and doctors work together to help children manage type 1 diabetes. About 30 kids will take part to see if the program is practical and well-liked. The goal is to improve daily diabetes care at school.

This study looks at whether allowing pregnant women with diabetes to have slightly higher blood sugar levels during labor can reduce the chance of their newborns having dangerously low blood sugar. Researchers will compare a more relaxed blood sugar target to the usual strict con…

This study aimed to see if romosozumab (Evenity) could improve bone density and muscle mass in postmenopausal women with osteoporosis who need spine surgery. Participants would have received either romosozumab or alendronate before surgery. However, the trial was withdrawn before…

This study tests whether giving time- and event-based cues (like alarms or visual reminders) helps people with schizophrenia or schizoaffective disorder remember to take their medication. 104 adults aged 18-60 with a schizophrenia diagnosis are taking part. The goal is to see if …

This study tests a program called Forging Hopeful Futures that teaches teens aged 13-19 about racial, gender, and economic fairness to help them avoid violence. About 720 teens from participating neighborhoods or schools will take part. Researchers will check if the program reduc…

This study tests whether a short computer-based cognitive training can enhance and extend the rapid antidepressant effects of ketamine or esketamine. Researchers will enroll 600 adults aged 18-80 with treatment-resistant depression who are already receiving ketamine as part of th…

This study tests a mobile cognitive-behavioral therapy program called MAAT to help breast cancer survivors who have memory and concentration problems after chemotherapy. About 220 survivors who finished chemo 1-5 years ago will either use MAAT or receive supportive therapy. The g…

This study is testing a family-focused therapy for families who lost a parent to suicide at least a year ago. It includes 30 families with children aged 8-14 who are struggling with prolonged grief. The therapy is done online and aims to reduce grief symptoms in both parents and …

This study tests whether adding a computer-based cognitive training program can improve depression relief for people already receiving esketamine treatment. Researchers will enroll up to 40 adults aged 18-80 at the University of Pittsburgh. The goal is to see if this approach can…

This study tests a program called Nae Disha for Life to see if it can reduce suicide thoughts in young people aged 12-17 in rural India. About 272 students from 4 schools will take part. The program teaches resilience and coping skills to help ease suicidal thoughts and anxiety.

This study looks at whether having surgery earlier or later, and starting rehab sooner or later, helps people with severe knee injuries recover faster. It includes 690 military personnel and civilians aged 16 to 55 with injuries to two or more knee ligaments. Participants are ran…

This study looks at whether a mindfulness program can improve attention and brain connectivity in 11-14 year olds who have a family history of mood disorders and high mood swings. About 224 teens will be randomly assigned to mindfulness or a health education class. The goal is to…

This study looks at two different strategies to get more veterans tested for colon and liver cancer: directly contacting people who need screening, or helping doctors fix delays. Researchers will compare how well each method works across many VA sites. The goal is to find the mos…

This study looks at whether a pharmacist's review that includes a person's genetic test results can lead to better medication outcomes and lower healthcare costs. About 600 employees from Pitt/UPMC who already had genetic testing will take part. Half will get a medication review …

This study follows 164 adults with dental implants for 15 months to see if bleeding when the dentist probes the gums can predict bone loss around the implant. Participants attend check-ups every 3 months, where the dentist measures bleeding and takes X-rays to track bone levels. …