Can palliative care help older ICU patients and their families?
NCT ID NCT04921631
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether adding specialty palliative care early on to standard intensive care can improve the experience for critically ill older adults (age 60+) and their families. Over 1,000 patients and their family members took part. The goal was to see if this approach leads to more patient-centered care and less distress for families.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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1,091 people
The number who actually took part.
- Started
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Jun 2021
- Finished
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Feb 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Patient Inclusion Criteria 1. Admitted to a participating study ICU 2. Age greater than or equal to 60 years 3. Meets one or more of the following acute or chronic triggers for PC consultation Acute: * Cardiac or respiratory arrest with coma * Ischemic or hemorrhagic stroke requiring mechanical ventilation * ICU admission after hospital stay of greater than or equal to 10 days or ICU readmission within 30 days * Age greater than or equal to 80 and 1 or more forms of organ support * Multiorgan system failure * CCM physician judgment of greater than or equal to 50% risk of in-hospital death or new severe long term functional impairment Chronic: * Admission from a SNF or LTACH with progressive functional decline * Metastatic (stage IV) cancer or advanced cancer without curative treatment * End stage cardiorespiratory disease * End stage liver disease * Advanced dementia or other end-stage neurologic disease * Age greater than or equal to 80 with two or more major comorbidities * Moderate-severe frailty (excluding stable intellectual or physical disability 1. Pittsburgh Cardiac Arrest Category (PCAC) greater than or equal to 2 2. Organ support: RRT, invasive or non-invasive mechanical ventilation, vasopressors 3. Sequential Organ Failure Assessment (SOFA) score greater than or equal to 10 4. Model for End-Stage Liver Disease (MELD) greater than or equal to 30 5. Major comorbidities defined by Charlson Co-morbidity Index (CCI) 6. Clinical Frailty Scale (CFS) score greater than or equal to 6 Patient Exclusion * No surrogate decision maker * Already received (or refused) a Palliative Care consultation during the same hospitalization * Determined to be imminently dying (within hours) by CCM physician * Within 1 year of receiving organ transplant, or actively undergoing work-up for organ transplant * Non-English speaking Surrogate Inclusion * Primary surrogate, as determined by the patient's advance directive or by the hierarchy codified in state law * Up to 3 additional surrogates Surrogate Exclusion * Age \<18 * Cannot read or understand English * Cannot complete surveys due to physical or cognitive limitations Clinician Inclusion •Patient's primary attending (or their designee)
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Pittsburgh
Pittsburgh, Pennsylvania, 15213, United States
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