University Of North Carolina, Chapel Hill

This study is testing a new, multi-session training program to help older adults with diabetes learn to use continuous glucose monitors (CGMs). It will compare this extended training to simpler, standard training methods. The goal is to see if more support helps people wear the d…

This study aims to find out if giving medication once a day through a chest tube works just as well as giving it twice a day for treating serious infections around the lungs. Researchers will randomly assign 270 hospitalized adults with these infections to receive the medication …

This study aims to find the best surgical method for people in Tanzania who need a second eyelid surgery due to trachoma complications. It will compare two different surgical techniques in 1,000 participants to see which one provides more successful, longer-lasting results. The g…

This study is testing a mobile phone tool to help community health workers provide better home check-ups for women after C-section surgery in rural Rwanda. The goal is to spot dangerous wound infections earlier, get women to care faster, and reduce health problems and financial h…

This study is testing whether a quick-dissolve film called BXCL501, given in the emergency room after a car accident, can reduce immediate stress reactions and prevent long-term PTSD symptoms. Researchers will enroll 100 adults who come to the ER within 24 hours of a car crash an…

This study is testing whether a liquid placed under the tongue (sublingual immunotherapy) can help children aged 1-11 become less sensitive to cashew nuts. Over 18 months, researchers will see if the treatment safely allows kids to tolerate small amounts of cashew without a serio…

This study aims to find out which newer medications work best and are safest for children with inflammatory bowel disease (IBD) when standard anti-TNF drugs have stopped working. It will follow about 1100 children and teens who are already starting one of these newer medications …

This study is testing a new way to prevent malaria in pregnant women by treating their entire household with anti-malaria drugs. Researchers want to see if creating a 'malaria-free zone' around pregnant women reduces their risk of infection. The pilot study in Uganda will involve…

This study aims to see if banning menthol cigarettes while also running a quit-smoking campaign helps people buy fewer tobacco products. Researchers will recruit about 1,185 U.S. adults who currently smoke menthol cigarettes. Participants will visit a simulated store twice, shop …

This small pilot study is testing if a brief, video-based sleep therapy can prevent PTSD and depression in people at high risk after a car accident. Researchers will enroll 20 adults who go to the emergency room after a crash and are sent home. The goal is to see if this approach…

This study is testing a personalized prenatal support program called PTBCARE+ to see if it can lower stress and reduce the risk of early delivery in pregnant people who are at high risk for having a preterm baby. Researchers will compare about 1,200 participants who receive the e…

This study is testing whether a special omega-3 dietary supplement can reduce chronic jaw pain and sensitivity in adults with temporomandibular disorder (TMD). One hundred participants will take either the supplement or a placebo pill daily for eight weeks while tracking their pa…

This small pilot study aims to prepare for future research comparing two common over-the-counter pain medications—ibuprofen and acetaminophen—for treating menstrual cramps in women with Crohn's disease. The study will enroll 24 women to test whether participants can follow the st…

This study is looking at whether putting warning labels on sugary drinks changes people's attitudes about weight and obesity. About 543 adults who recently bought sugary drinks will visit a mock store four times. They will be randomly shown either regular labels or new warning la…

This study is testing whether a 6-session virtual parenting program can help parents feel more confident and knowledgeable about raising their teenager. Researchers will compare 60 parents who take the class right away to those who wait. The goal is to see if the program improves…

This study aims to see if a special fortified porridge for gut health and a training program for caregivers can improve early learning and brain development in young children in rural Guatemala. Researchers will follow 400 mother-child pairs, starting when the child is 6 months o…