University Of North Carolina, Chapel Hill
Clinical trials sponsored by University Of North Carolina, Chapel Hill, explained in plain language.
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Fish oil and vitamin d tested to stop chronic burn pain
Prevention TerminatedThis study looked at whether taking fish oil and vitamin D soon after a burn injury could stop chronic pain from developing. It included 24 adults with burns covering less than 30% of their body. The trial was stopped early, so results are limited.
Phase: PHASE2 • Sponsor: University of North Carolina, Chapel Hill • Aim: Prevention
Last updated May 20, 2026 11:54 UTC
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Mindfulness app aims to ease anxiety in underserved communities
Symptom relief TerminatedThis study tested a smartphone app called SMILE that teaches mindfulness to help reduce anxiety. It included 398 Black and Latino adults who had moderate anxiety. Participants used the app for 8 weeks and reported their stress levels and heart activity. The goal was to see if the…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated May 26, 2026 03:04 UTC
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Can a nasal device boost mood? small study investigates
Symptom relief TerminatedThis study looked at whether using the SinuSonic device for 5 weeks could improve anxiety, depression, and overall well-being in adults with ongoing nasal or sinus congestion. Sixteen participants tracked their symptoms and device use. The study was terminated early, so results a…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated May 26, 2026 02:51 UTC
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Brain zaps and bad habits: tiny study halted early
Knowledge-focused TerminatedThis study looked at whether a single session of non-invasive brain stimulation (alpha-tACS) could make people more flexible in their choices, especially those with a history of heavy drinking. Only 7 healthy adults and risky drinkers took part before the study was stopped. Resea…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 26, 2026 02:54 UTC
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Can video coaching boost vaccine talks in rural pharmacies?
Knowledge-focused TerminatedThis study looked at whether virtual coaching helps rural pharmacists better counsel patients who are hesitant about COVID-19 vaccines. Sixteen pharmacies took part, first receiving standard training and then adding a virtual coach. Researchers measured how well pharmacists commu…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 26, 2026 02:54 UTC
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Blood test may predict vasculitis relapse, study hints
Knowledge-focused TerminatedThis study looked at whether measuring certain immune cells (CD5+ regulatory B cells) after initial treatment could help doctors decide who needs ongoing therapy for ANCA vasculitis, a rare blood vessel disease. The idea was that patients whose immune cells recovered well might s…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 26, 2026 02:51 UTC
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Brain injury drug study halted after just 5 patients
Knowledge-focused TerminatedThis small pilot study aimed to see if antiseizure medications change brain connectivity patterns in people with severe brain injuries who are unconscious. Only 5 participants were enrolled before the study was stopped early. Researchers used brain scans to look for seizure-relat…
Phase: PHASE4 • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 26, 2026 02:47 UTC
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Digital tool for psychosis care: what helps or hinders its use?
Knowledge-focused TerminatedThis study aimed to understand what helps or gets in the way of using Horyzons, a digital platform with therapy and social features, in clinics for young people with early psychosis. Researchers recruited providers and clients from five clinics in North Carolina and gathered feed…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC
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Xenon MRI aims to spot 'Good' fat in obesity fight
Knowledge-focused TerminatedThis early-phase study tested whether a special MRI technique using inhaled xenon gas could detect brown adipose tissue (BAT) in healthy adults. Brown fat helps burn calories, so finding it could improve understanding of obesity. The study involved 17 volunteers and measured BAT …
Phase: PHASE1 • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 20, 2026 12:08 UTC
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Virtual reality training aims to make maternity care more equitable
Knowledge-focused TerminatedThis study tested a virtual reality training program for healthcare teams to reduce disparities in maternal care. It involved 66 participants, including healthcare workers and new mothers. The goal was to see if the training could lower severe postpartum pain and improve respectf…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 19, 2026 11:46 UTC