University Of Bern

This study is testing if adding a once-weekly medication called tirzepatide to automated insulin pump therapy helps adults with type 1 diabetes manage their blood sugar better. Researchers will compare the new combination to standard insulin pump therapy alone in 42 participants …

This study aims to see if combining antidepressant medication with a community-based talk therapy program works better than talk therapy alone for adults with moderate to severe depression in Zimbabwe. It will involve 296 participants who will be randomly assigned to receive eith…

This study is testing whether a smartphone app can help young people (ages 14-35) who are already in treatment for alcohol or cocaine use disorder. The app provides short brain-training games designed to strengthen a person's ability to ignore or resist substance-related cues and…

This study is testing the early feasibility of a new automated insulin delivery system for adults with Type 1 diabetes. A smartphone app will use data from a glucose sensor to automatically control an insulin pump. The goal is to see if this 'hybrid closed-loop' system works reli…

This study is testing whether a chewing gum containing a special fiber (GOS) can help overweight adults manage their weight and improve their metabolism. Researchers will enroll 120 participants to see if using the gum affects their body mass index (BMI), blood pressure, blood su…

This study compares two established surgical methods for building up soft gum tissue in areas where a tooth is missing. Researchers will measure how much volume each graft material adds over time and check patient satisfaction. The goal is to gather better data to help dentists c…

This study is comparing two surgical methods to treat receding gums in people who have had orthodontic treatment (braces). The standard method uses a small graft of tissue taken from the roof of the patient's mouth. The new method uses a ready-made collagen patch instead, which a…

This study aims to develop a smartphone app to help treat depression. Researchers want to see if suggesting small, personalized daily activities (like taking a short walk) can boost people's energy and improve their mood. They are recruiting 180 adults with depression to test how…

This study is testing a new design for a dental bridge that replaces three missing back teeth using only one dental implant. Researchers want to see how well this new 'T-Bridge' holds up over time and if it causes any problems. The trial is recruiting 50 adults who are missing th…

This study is testing a new program to help family doctors safely stop or reduce the dose of stomach acid medications (PPIs) when patients no longer need them. It will involve 400 adults in Switzerland who are taking these drugs long-term without a clear medical reason. The goal …

This study compares two surgical methods for treating bone loss caused by advanced gum disease. Researchers will test a new collagen matrix material against a standard bone graft material in 80 patients over 12 months. The goal is to see which approach better helps gums reattach …

This study is testing whether following a modified ketogenic diet (a high-fat, low-carb eating plan) can help people with alcohol use disorder drink less alcohol. Researchers will work with 50 adults currently undergoing standard alcohol withdrawal treatment. Half will receive sp…

This study examines whether placing an artificial tooth immediately after dental implant surgery works as well as waiting four weeks. Researchers will compare both approaches in 100 people who need a lower back molar replaced. The goal is to determine if immediate placement leads…

This study aims to see if sensors in a car can detect when a driver is impaired by cannabis. Researchers will have 45 healthy, regular cannabis users drive on a closed track, some after consuming cannabis, to collect data on driving behavior, eye movements, and body signals. They…

This study is testing different versions of a short, one-hour online program designed to help people manage symptoms of depression and anxiety while they wait for a regular therapy appointment. Researchers will compare eight different versions of the program to see which combinat…

This study aims to understand if the chemicals in a person's exhaled breath change in a daily pattern and if these patterns differ between people without diabetes, with type 1 diabetes, and with type 2 diabetes. Researchers will recruit 60 participants to provide breath samples d…

This study aims to understand how a brief, specialized therapy called ASSIP affects the thought patterns of people who have attempted suicide. Researchers will compare ASSIP to standard care by measuring things like impulse control and feelings of self-efficacy. The goal is to le…

This study is a national patient registry, not a treatment trial. It aims to collect long-term health information from up to 800 people in Switzerland who have Primary Ciliary Dyskinesia (PCD), a rare genetic condition affecting the lungs and sinuses. By tracking symptoms, treatm…

This study is creating a national registry to collect information on the diagnosis, treatment, and daily life of people with cerebral palsy in Switzerland. It aims to enroll 15,000 children and adults to better understand the condition, its causes, and how care can be improved. T…

This project is creating a national registry to collect information about people in Switzerland who have a rare disease. The goal is to gather data to better understand these conditions, improve healthcare, and connect patients to research opportunities. It aims to enroll up to 5…

This study aims to understand how common a serious fatty liver disease (MASLD) is in people who survived breast or colorectal cancer 5-10 years ago. Researchers will use newer, less painful scanning methods instead of a biopsy to check 200 participants for signs of liver damage. …

This study aims to understand the brain activity and psychological differences between people who have attempted suicide, those who have suicidal thoughts, other psychiatric patients, and healthy individuals. Researchers will compare 180 participants across these four groups usin…

This study aims to understand why some people develop persistent health problems after receiving a COVID-19 vaccine, a condition known as Post-Acute COVID-19 Vaccination Syndrome (PACVS). Researchers will track 200 participants' symptoms over eight months and test their blood for…

This project is a national registry in Switzerland that collects health information from people with rare neuromuscular diseases like Duchenne muscular dystrophy and spinal muscular atrophy. It aims to connect patients to new treatment trials, help researchers understand these di…

This study aims to better understand the ear, nose, and throat (ENT) problems experienced by people with Primary Ciliary Dyskinesia (PCD), a rare genetic condition that affects the lungs and sinuses. Researchers will observe 1000 patients at clinics worldwide during their regular…

This study aims to understand how a safe, mild form of electrical brain stimulation affects how people think and process information. Researchers will compare healthy younger adults (20-40) and older adults (60-80) as they do computer tasks, using MRI scans to see how their brain…

This study aims to understand the long-term health effects that childhood cancer survivors experience years after their treatment ends. Researchers will follow 3,000 survivors in Switzerland, collecting health data from check-ups, tests, and questionnaires during their regular fo…

This study aims to learn more about primary ciliary dyskinesia (PCD) by gathering information directly from people who live with it. Anyone, anywhere in the world, with suspected or confirmed PCD can join by completing online questionnaires about their symptoms, treatments, and d…

This study aims to understand why cervical pre-cancer sometimes returns after treatment in women living with HIV, a group at very high risk for cervical cancer. Researchers will follow 250 women in Zimbabwe for two years after their treatment to see how often the disease comes ba…