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Can your own blood help save a failing dental implant?

NCT ID NCT06679283

First seen Apr 08, 2026 · Last updated Jun 23, 2026 · Updated 9 times

Summary

This study tests whether adding platelet-rich fibrin (PRF), made from a patient's own blood, to standard surgery improves healing of bone and gum damage around dental implants. Forty adults with peri-implantitis will be randomly assigned to receive either surgery with PRF or surgery alone. After 12 months, X-rays and clinical exams will compare bone fill and pocket depth between the two groups.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Periodontology, University of Bern

    RECRUITING

    Bern, 3010, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

platelet-rich fibrin (PRF)

What this could lead to

If it works, this could point toward a better treatment for peri-implantitis, helping to save implants and reduce bone loss.

What could go wrong

This is a small, early-stage trial with only 40 participants, so results may not apply widely. PRF may not provide extra benefit over standard surgery.

Conditions

The condition(s) this trial relates to.

bone resorption disease Peri-Implantitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.