University Medical Center Groningen

This large, late-stage trial is testing whether the drug dapagliflozin can help protect the heart and kidneys in people with very advanced chronic kidney disease, including those on dialysis or with a kidney transplant. About 1,750 participants will take either dapagliflozin or a…

This study is testing whether a daily pill called finerenone can help slow the progression of chronic kidney disease in adults who are not taking a common class of kidney-protective drugs (RAS inhibitors). About 180 participants will be randomly assigned to take either finerenone…

This research study aims to understand how the immune system in the gut changes when cancer patients receive immunotherapy. Researchers will collect small tissue samples from the lower intestine and blood samples from 38 participants before and during their immunotherapy treatmen…

This study is testing a new type of PET/CT scan that uses a special tracer to look at a protein called PD-L1 in the body. Researchers want to see if this scan can help predict which patients with large B-cell lymphoma will respond well to CAR-T cell therapy. The study also aims t…

This study aims to understand why men who have been successfully treated for testicular cancer face a higher risk of developing heart disease later in life. Researchers are observing 939 survivors to identify the specific risk factors, such as past chemotherapy or lifestyle facto…

This study aims to understand why some cancer patients develop severe heart or lung problems from certain chemotherapy drugs while others don't. Researchers will take skin cells from 20 former cancer patients who either had severe reactions or no reactions to treatment and turn t…