University Medical Center Groningen

This early-phase study tested a vaccine called DCP-001 in 17 women with a specific type of ovarian cancer (high-grade serous) who had already completed standard treatment. The goal was to see if the vaccine is safe and can boost the immune system to recognize and fight cancer cel…

This study looked at whether a low dose of the cheap, old heart drug digoxin can help people with chronic heart failure. About 982 adults with heart failure and reduced pumping ability took either digoxin or a placebo. The goal was to see if digoxin lowers the chance of heart fai…

This pilot study tested whether people with type 2 diabetes and early kidney disease can take part in a clinical trial from home. Twelve participants collected their own urine, blood, and blood pressure readings remotely. They took empagliflozin first, and based on their response…

This study tested a computer tool called MuSt-PC that helps doctors and nurses make better care decisions for adults with serious illnesses like cancer or heart failure. The goal was to see if patients could complete the required surveys and if the tool was helpful. 44 patients w…

This study tested a tool called MuSt-PC that helps doctors manage multiple symptoms in patients receiving palliative care. The goal was to see if the tool is easy to use and helpful for improving quality of life. 70 healthcare workers, including doctors and nurses, participated. …

This study tested a smartphone app called Compas-Y, designed to help people with cancer manage emotional distress. Twenty-eight adults who had finished cancer treatment and felt low well-being used the app for 6 weeks. Researchers measured changes in self-compassion, self-critici…

This study tested a computer model (Eleveld) to find the right propofol dose for different levels of deep sedation in 75 adults. Researchers measured sedation depth using standard scores and brain monitoring. The goal was to improve dosing accuracy and safety during procedures.

This study looked at whether a certain type of immune cell (cytotoxic CD4+ T cells) is connected to fatigue in people with multiple sclerosis (MS). 34 adults with MS took part. Researchers measured fatigue using questionnaires and physical tasks, then checked blood samples for th…

This study tested a new imaging technique to see a protein called PD-L1 in esophageal cancer tumors. PD-L1 helps doctors decide if immunotherapy might work, but current tests are not always accurate. Researchers gave 21 patients a special fluorescent dye that attaches to PD-L1, t…

This study looked at how the COVID-19 pandemic changed healthcare and affected the quality of life of over 5,000 Dutch patients who had surgery or another medical procedure in 2020-2021. Researchers created a survey to capture patients' experiences and linked their answers to nat…

This study followed 72 kidney and lung transplant patients for one year to see how hand tremors caused by anti-rejection drugs change over time. Researchers used spiral drawings and wrist-worn sensors to measure tremor severity. The goal was to better understand this common side …

This study checked over 4,000 ICU patients for undiagnosed diabetes and prediabetes using a blood test (HbA1c). It found that many patients had these conditions without knowing, and that these hidden blood sugar problems were linked to higher risks of organ failure and death. The…

This study looked at whether using a 3D map of the heart helps doctors deliver pulsed field ablation more accurately for atrial fibrillation. 32 adults with AF were randomly assigned to get ablation with or without the 3D map. The goal was to see if the 3D map leads to better-qua…

This study looked at whether special communication training for pharmacists and general physicians helps them safely reduce or stop heart and diabetes medications in older patients (75+). Researchers compared trained vs. untrained healthcare teams and tracked how many patients ha…

This study looked at 807 adults with adrenal tumors found by chance during scans for other reasons. Researchers compared the standard approach of repeated CT scans with a single urine test to see which was more cost-effective for detecting cancer. The goal was to find a simpler, …