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Testicular cancer survivors face hidden heart risks – study seeks answers

NCT ID NCT02276430

Knowledge-focused Sponsor: University Medical Center Groningen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study follows nearly 1,000 testicular cancer survivors to understand why they have a higher risk of heart disease. Researchers are looking at how cancer treatments like chemotherapy may damage blood vessels or lead to risk factors like high blood pressure. The goal is to improve long-term care for young men who beat testicular cancer.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify which testicular cancer survivors are at higher risk for heart disease and create better follow-up care plans.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly change patient care. Results may take years to influence guidelines.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

939 people

The number who actually took part.

Start date

Jul 2014

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Testicular cancer survivors

Ages

18 to 75 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

All participating patients have to meet the following criteria: * Alive * TC diagnosis between 01-01-1976 to 31-12-2007 * TC treatment center: UMCG, NKI/AVL, Erasmus MC, UMCN, LUMC * Younger than 50 years of age at TC diagnosis * Written informed consent Cases have to fulfill, beside the aforementioned criteria, the following criteria: * Diagnosed with either myocardial infarction (MI), proven coronary artery disease (CAD) (CTCAE-4 grade 2 or higher) or congestive heart failure (CHF) (CTCAE-4 grade 2 or higher). * No medical history of CVD before diagnosis of TC In order to be eligible to participate in the cardiometabolic risk inventory study (and to be invited to a study assessment), a subject must meet, next to the criteria mentioned in "1)", the following inclusion criteria: * Younger than 40 years of age at TC diagnosis * Younger than 75 years of age at moment of inclusion Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: * Mental disorder (no informed consent available) * Presence of active malignant disease

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder testicular cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Testicular cancer

Contacts and locations

Locations

  • Antoni van Leeuwenhoek Hospital

    Amsterdam, Netherlands

  • University Medical Center Groningen

    Groningen, 9700 RB, Netherlands

  • University Medical Center St. Radboud

    Nijmegen, Netherlands

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