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Immunotherapy before surgery shows promise for aggressive uterine cancer

NCT ID NCT06180733

First seen May 13, 2026 · Last updated May 22, 2026 · Updated 4 times

Summary

This study tests whether giving the immunotherapy drug pembrolizumab before standard hysterectomy can shrink tumors in people with a specific type of uterine cancer (MMRd). Twelve participants will receive 9 cycles of pembrolizumab, then have surgery as planned. The goal is to see how many achieve a major response in the tumor tissue, which could lead to a larger trial comparing this approach to standard care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University Medical Centre Groningen

    Groningen, Provincie Groningen, 9700 RB, Netherlands

Conditions

Explore the condition pages connected to this study.