University Hospital, Tours

This pilot study is looking for specific markers in blood platelets that could help doctors diagnose ALS (Lou Gehrig's disease) more accurately and quickly. Researchers will compare 60 participants—30 with early ALS and 30 with other motor neuron diseases—to find unique platelet …

This study looks at whether a special brain ultrasound can help doctors decide which patients with suspected normal pressure hydrocephalus will benefit from a shunt surgery. About 110 adults will get the ultrasound before a standard spinal tap, and their progress will be checked …

This study tests whether taking propranolol, a drug usually used for high blood pressure, soon after a sexual assault can prevent post-traumatic stress disorder (PTSD). 34 adult women will receive either propranolol or a placebo for 10 days, then a lower dose for another 14 days.…

This study tests a new high-tech device that uses eye-tracking to help patients in the intensive care unit (ICU) who are on breathing machines communicate. Many of these patients are awake but cannot speak due to tubes, leading to frustration and anxiety. The device lets them sel…

This study tests whether dexmedetomidine, a sedative drug, can lower the chance of delirium (confusion and agitation) in children who need a breathing machine in the intensive care unit. About 266 children, aged 1 month to 17 years, will be randomly assigned to receive either dex…

This study tests whether playing personalized music through a sound shower in the ICU waiting room can reduce anxiety for family members of critically ill patients. About 224 adult relatives of intubated patients will be randomly assigned to a waiting room with or without music. …

This study aims to create a detailed atlas of ultrasound images of the mouth. Researchers will scan the mouths of 100 adult dental patients to capture pictures of normal and diseased tissues. The goal is to help dentists use ultrasound as a safe, radiation-free tool for diagnosis…

This study aims to find out how often people with ADHD also have fibromyalgia, and vice versa. Researchers will also look for biological markers in the blood. About 100 adults will take part, including those with ADHD (some on medication, some not) and those with fibromyalgia. No…

This study looks at whether common chemicals found in plastics, non-stick coatings, and pesticides are linked to obesity in children. Researchers will measure levels of these chemicals in the blood of 80 children aged 6 to 15, comparing those with obesity to those without. The go…

This observational study looks at how the brain responds to different senses (like sight and sound) in 200 children and adults with and without neurodevelopmental disorders. Participants will have their brain activity recorded, take behavioral tests, and do learning exercises at …

This study will gather information from 10,000 people who have a spontaneous brain hemorrhage (bleeding in the brain). Researchers will collect medical history, brain scans, and blood samples to better understand the condition and find ways to improve diagnosis and treatment. The…

This study looks at 149 adults with early-treated phenylketonuria (PKU) to find connections between their genes, blood chemistry, and health. Researchers will analyze DNA from saliva and metabolites from blood samples. The goal is to better understand PKU, not to test a new treat…

This study looks at immune cells in sputum (phlegm) and blood samples from 50 adults with advanced lung cancer who are starting immunotherapy. Researchers want to see if changes in these cells can predict how well the treatment works. The goal is to find better ways to identify w…