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Can a simple oxygen trick prevent dangerous drops during intubation?

NCT ID NCT07189338

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 31 times

Summary

This study tests whether giving extra oxygen through the nose during the brief pause between stopping a breathing mask and placing a breathing tube can prevent severe drops in oxygen levels. About 500 ICU patients with low oxygen due to lung failure will be randomly assigned to receive this extra oxygen or standard care. The goal is to see if the extra oxygen reduces the risk of oxygen levels falling below 80% during the procedure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHRU de Tours

    Tours, 37000, France

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

High-flow nasal oxygen (HFNO) during intubation

What this could lead to

If it works, this could make intubation safer for critically ill patients by preventing dangerously low oxygen levels.

What could go wrong

This is an early-stage procedure trial with no phase, and the benefit may be small or not apply to all patients. Risks include device-related complications.

Conditions

The condition(s) this trial relates to.

acute respiratory failure respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.