Heart drug may stop PTSD before it starts in sexual assault survivors

NCT ID NCT07452978

Not yet recruiting Prevention Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

First seen Mar 11, 2026 · Last updated Jun 13, 2026 · Updated 17 times

Summary

This study tests whether giving the drug propranolol (a beta-blocker) soon after a sexual assault can prevent post-traumatic stress disorder (PTSD). 34 adult women who seek help within 72 hours will take either propranolol or a placebo for 10 days, then a lower dose for another 14 days. Researchers will check for PTSD symptoms at 5 weeks using a standard interview. The idea is that propranolol may weaken the traumatic memory during its reconsolidation phase, reducing the risk of developing PTSD.

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Conditions

The condition(s) this trial relates to.

combat disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PTSD - POST TRAUMATIC STRESS DISORDER