Blood platelets may hold key to faster ALS diagnosis
NCT ID NCT07479017
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to find specific markers in blood platelets that can help doctors diagnose ALS (Lou Gehrig's disease) more accurately and earlier. Researchers will compare 60 participants—30 with newly diagnosed ALS and 30 with other motor neuron diseases—to see if platelet tests can tell them apart. The goal is to develop a routine blood test that speeds up diagnosis and treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with ALS or another MND followed in 3 ALS centers
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Patients with ALS: * Men or women aged 18 to 75 * ALS diagnosed according to the El Escorial criteria * ALS diagnosis less than 3 months ago * Onset of symptoms defined as the time when muscle weakness was first observed by the patient less than 2 years ago Controls with another motor neuron disease: * Men or women aged 18 to 75 * Diagnosis of motor neuron disease \< 3 months Exclusion Criteria: * Genetic variants associated with ALS * Pregnant or breastfeeding women * Treatment with oral or injectable anticoagulants, antiplatelet agents (EXCEPT aspirin at the maximum authorized dosage of 160 mg per day) * Uncontrolled diabetes * Persons deprived of their liberty by judicial or administrative decision * Persons subject to legal protection measures: guardianship or curatorship * Opposition to data processing
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University hospital, Limoges
Limoges, 87000, France
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University hospital, Lyon
Lyon, 69000, France
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university hospital, Tours
Tours, 37044, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Ultra-Strong MRI scans could spot ALS earlier
- Can a blood bank unlock the genetics of brain disease?
- Blood markers may unlock early ALS detection — a study puts them to the test
- Brain implant aims to give voice to those trapped in silence
- Nasal spray aims to tame brain inflammation in ALS