The First Affiliated Hospital With Nanjing Medical University

This study is testing a multi-step treatment plan for people with a type of advanced bile duct cancer that cannot be surgically removed. The goal is to use a combination of immunotherapy, chemotherapy, and radiation to shrink the tumor and control the disease so that patients can…

This study is testing a new combination of two immunotherapy drugs (iparomlimab and tuvonralimab, together called QL1706) with a modified chemotherapy regimen (TFOX) for people with advanced stomach or gastroesophageal junction cancer that is HER2-negative. The goal is to see if …

This study is looking at a procedure called intravascular lithotripsy (IVL) for people with severe calcium buildup in their heart arteries. The procedure uses a special balloon to break up the hard calcium so that a stent can be placed more effectively. Researchers will follow 20…

This study is testing a combination of two immunotherapy drugs, one targeted therapy drug, and a standard chemotherapy regimen. The goal is to see if this four-drug combination can shrink tumors enough to allow for surgical removal in patients with a specific type of advanced sto…

This study aims to find out which of two different chemotherapy combinations works better for people whose diffuse large B-cell lymphoma has come back more than a year after initial treatment. About 70 participants will be randomly assigned to receive one of the two drug regimens…

This study is testing whether adding one or two new drugs to standard chemotherapy before surgery can better shrink tumors in people with advanced stomach or gastroesophageal cancer. The goal is to see if this approach helps more patients have no cancer cells left in the removed …

This study is testing whether a new combination of drugs works better for people with advanced soft tissue sarcoma that cannot be removed by surgery. About 46 participants will receive a targeted therapy drug (anlotinib) plus an immunotherapy drug (bempegaldesleukin) along with s…

This study is testing if adding a drug called nimotuzumab to standard chemotherapy helps people with high-risk pancreatic cancer that can be removed by surgery. About 156 patients will receive the drug combination or a placebo before and after their operation. The main goal is to…

This early study aims to find a safe dose of an experimental cell therapy called LV009 for adults whose CD19-positive blood cancers have returned or not responded to standard treatments. Researchers will give LV009 to up to 19 participants and closely monitor them for side effect…

This early-stage study is testing whether transplanting lab-grown retinal cells into the eye is safe and might help improve vision in people with late-stage age-related macular degeneration (AMD). It will involve 9 participants with significant vision loss to first check for safe…

This study aims to find out if robot-assisted surgery helps people with advanced stomach cancer live longer without their cancer returning, compared to traditional laparoscopic (keyhole) surgery. About 335 adults with a specific stage of stomach cancer will be randomly assigned t…

This study is testing whether adding a new immunotherapy drug called QL1706 to standard chemotherapy before stomach cancer surgery works better than chemotherapy alone. The goal is to shrink tumors more effectively before surgery, potentially leading to better long-term outcomes.…

This study is testing whether adding a targeted drug called brentuximab vedotin to standard chemotherapy works better for people newly diagnosed with a specific type of lymphoma linked to the Epstein-Barr virus (EBV). Researchers want to see if this combination is safe and can he…

This study is testing if a new 7-day treatment for a common stomach bacteria (H. pylori) works as well as the current 14-day standard. Researchers are adding a bismuth medication to a two-drug combo to see if it makes the shorter course effective. The goal is to find a faster, ea…

This study is testing whether a drug called SHR2554 can help prevent cancer from coming back in people with peripheral T-cell lymphoma (PTCL) who have already responded to their first treatment. It will enroll about 30 adults who achieved a partial or complete response after init…

This study aims to find out which of two modern, minimally invasive spine surgeries works better for middle-aged and older adults with lumbar spinal stenosis, a common cause of severe back and leg pain. Researchers will randomly assign 176 participants to receive either a simpler…

This study is testing a new robotic surgery technique to remove excess breast tissue in men with gynecomastia (enlarged male breasts). Researchers will evaluate how well the single-port robotic system works and how safe it is for this procedure. They'll measure patient satisfacti…

This study is testing if a new anesthesia drug called remimazolam can reduce confusion (postoperative delirium) in patients 65 and older after stomach cancer surgery. It will compare remimazolam against a standard anesthesia mix in 170 patients. The main goal is to see if the new…

This study is testing if adding a drug called megestrol acetate helps patients with advanced stomach cancer maintain their weight and appetite while they receive strong pre-surgery treatment. It will involve 48 patients who have significant weight loss (cachexia). Half will get t…

This study is testing whether a combination of two sedative drugs, esketamine and dexmedetomidine, can better manage severe agitation and confusion (delirium) in intensive care unit (ICU) patients who are awake and on breathing support but not on a ventilator. The main goal is to…

This study aims to find out if a newer, less invasive endoscopic surgery helps women regain feeling in their breast skin better than the standard surgery after a nipple-sparing mastectomy and implant reconstruction for early-stage breast cancer. Researchers will randomly assign 1…

This study aims to understand why some people with liver cirrhosis develop brain fog, known as hepatic encephalopathy. Researchers will compare 32 patients with and without this brain fog by analyzing their blood proteins and gut bacteria. The goal is to find biological clues tha…