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New drug cocktail aims to quiet ICU delirium faster

NCT ID NCT07377981

First seen Feb 01, 2026 · Last updated May 23, 2026 · Updated 16 times

Summary

This study tests whether combining two sedative drugs (esketamine and dexmedetomidine) can safely reduce the time ICU patients spend in a confused, agitated state called hyperactive delirium. About 132 adults on non-invasive breathing support will receive either the drug combo or standard care. The goal is to shorten delirium and lower the need for a breathing tube.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital with Nanjing Medical University

    Nanjing, Jiangsu, 210000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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